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©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Dec 26, 2022; 10(36): 13239-13249
Published online Dec 26, 2022. doi: 10.12998/wjcc.v10.i36.13239
Published online Dec 26, 2022. doi: 10.12998/wjcc.v10.i36.13239
Analysis of the clinical efficacy of two-stage revision surgery in the treatment of periprosthetic joint infection in the knee: A retrospective study
Yong-Jie Qiao, Xin-Yuan Yu, Hao-Qiang Zhang, Wen-Bin Yang, Xiao-Yang Song, Rui-Ling Xu, Sheng-Hu Zhou, Department of Joint Surgery, The 940th Hospital of Joint Logistic Support Force of Chinese People’s Liberation Army, Lanzhou 730050, Gansu Province, China
Feng Li, Department of Orthopedics, The 943rd Hospital of Joint Logistic Support Force of Chinese People’s Liberation Army, Wuwei 733000, Gansu Province, China
Lv-Dan Zhang, Department of Respiratory Medicine, The 940th Hospital of Joint Logistic Support Force of Chinese People’s Liberation Army, Lanzhou 730050, Gansu Province, China
Author contributions: Qiao YJ, Li F and Zhang LD contributed equally to this work; Qiao YJ, Li F and Zhang LD designed the study, collected data, performed the statistical analysis, and wrote the manuscript; Zhang HQ and Yu XY assisted with data collection; Yang WB drafted the manuscript; Zhang HQ and Song XY helped with data interpretation and critically reviewed the manuscript; Zhou SH conceived of the study, helped with data interpretation, and critically reviewed the manuscript; All the authors read and approved the final manuscript.
Institutional review board statement: Formal institutional approval was not deemed necessary since anonymised data routinely collected in our centre for clinical practice purposes were used.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: Participants gave informed consent for data sharing.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Sheng-Hu Zhou, PhD, Doctor, Department of Joint Surgery, The 940th Hospital of Joint Logistic Support Force of Chinese People’s Liberation Army, No. 333 Nanbinghe Road, Qilihe District, Lanzhou 730050, Gansu Province, China.
Received: August 10, 2022
Peer-review started: August 10, 2022
First decision: November 11, 2022
Revised: November 15, 2022
Accepted: December 5, 2022
Article in press: December 5, 2022
Published online: December 26, 2022
Processing time: 138 Days and 10.7 Hours
Peer-review started: August 10, 2022
First decision: November 11, 2022
Revised: November 15, 2022
Accepted: December 5, 2022
Article in press: December 5, 2022
Published online: December 26, 2022
Processing time: 138 Days and 10.7 Hours
Core Tip
Core Tip: The two-stage revision surgery approach, which includes the first stage of thorough debridement, removal of prosthesis, antibiotic bone cement placeholder exclusion for 3–6 mo, three normal consecutive routine blood examination results for erythrocyte sedimentation rate and C-reactive protein, selection of a suitable prosthesis for the second-stage revision, and the use of a sufficient amount of a full course of sensitive antibiotics, is a reliable method for the treatment of periprosthetic joint infection after total knee arthroplasty A. This approach can effectively relieve pain, control infection, and preserve good joint function.