Deng YF, Wu LP, Liu YP. Probiotics for preventing gestational diabetes in overweight or obese pregnant women: A review. World J Clin Cases 2022; 10(36): 13189-13199 [PMID: 36683622 DOI: 10.12998/wjcc.v10.i36.13189]
Corresponding Author of This Article
Yan-Ping Liu, MSN, Occupational Physician, Department of Clinical Nutrition, Chinese Academy of Medical Sciences and Peking Union Medical College Hospital, No. 1, Shuaifuyuan, Dongcheng District, Beijing 100730, China. liuyp1227@vip.sina.com
Research Domain of This Article
Obstetrics & Gynecology
Article-Type of This Article
Minireviews
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Dec 26, 2022; 10(36): 13189-13199 Published online Dec 26, 2022. doi: 10.12998/wjcc.v10.i36.13189
Probiotics for preventing gestational diabetes in overweight or obese pregnant women: A review
Ya-Fang Deng, Li-Ping Wu, Yan-Ping Liu
Ya-Fang Deng, Li-Ping Wu, Chinese Academy of Medical Sciences and Peking Union Medical College, School of Nursing, Beijing 100730, China
Yan-Ping Liu, Department of Clinical Nutrition, Chinese Academy of Medical Sciences and Peking Union Medical College Hospital, Beijing 100730, China
Author contributions: All authors conceptualized the idea of the article; Deng YF contributed to manuscript drafting, organized data, and reviewed the literature; and all authors contributed to revising the paper and approved the final publishing.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yan-Ping Liu, MSN, Occupational Physician, Department of Clinical Nutrition, Chinese Academy of Medical Sciences and Peking Union Medical College Hospital, No. 1, Shuaifuyuan, Dongcheng District, Beijing 100730, China. liuyp1227@vip.sina.com
Received: September 17, 2022 Peer-review started: September 17, 2022 First decision: October 30, 2022 Revised: November 12, 2022 Accepted: December 8, 2022 Article in press: December 8, 2022 Published online: December 26, 2022 Processing time: 100 Days and 5 Hours
Core Tip
Core Tip: The occurrence and progression of gestational diabetes mellitus (GDM) are associated with intestinal microbiota disorder. Probiotics modulate the gut microbiota, which can decrease lipopolysaccharide-containing microbiota in the gut and plasma lipopolysaccharides, and inhibit expression of inflammatory factors, thereby reducing insulin resistance, modulating glucose metabolism, and preventing GDM, especially in high-risk groups such as overweight/obese pregnant women. This review provides up-to-date evidence on the effects of probiotics in preventing GDM and improving glucose metabolism and other maternal and infant outcomes in overweight/obese pregnant women, and discusses the mechanism of probiotics on GDM, and the dose, method, and duration of probiotics use.
