Observational Study
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Nov 26, 2022; 10(33): 12175-12183
Published online Nov 26, 2022. doi: 10.12998/wjcc.v10.i33.12175
Prognostic values of optic nerve sheath diameter for comatose patients with acute stroke: An observational study
Sha Zhu, Chao Cheng, Liu-Liu Wang, Dian-Jiang Zhao, Yuan-Li Zhao, Xian-Zeng Liu
Sha Zhu, Xian-Zeng Liu, Department of Neurology, Peking university international hospital, Beijing 102206, China
Chao Cheng, Dian-Jiang Zhao, Department of Radiology, Peking University International Hospital, Beijing 102206, China
Liu-Liu Wang, Department of Intensive Care Unit, Peking University International Hospital, Beijing 102206, China
Yuan-Li Zhao, Department of Neurosurgery, China National Clinical Research Center for Neurological Diseases, Beijing Tiantan Hospital, Beijing 100070, China
Author contributions: Zhu S participated in the design of the study, analysis of the data, and drafting of the manuscript; Cheng C, and Zhao DJ participated in measuring optic nerve sheath diameter and eyeball transverse diameter; Wang LL contributed to the collection of clinical data; Zhao YL contributed to the guidance of the research; Liu XZ contributed to the guidance of the research and review of the manuscript; The author(s) have read and approved the final version of the manuscript.
Institutional review board statement: This retrospective study was approved by the Ethics Committee of Peking University International Hospital [Approval No. 2021-001 (BMR)].
Informed consent statement: Patients were not required to give informed consent to the study because the analysis used anonymous clinical data that were obtained after each patient agreed to treatment by written consent.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: If there is a need, you can find the corresponding author to share data at any time.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xian-Zeng Liu, PhD, Professor, Department of Neurology, Peking University International Hospital, No. 1 Life Science Park Life Road, Changping District, Beijing 102206, China. liuxianzeng@pkuih.edu.cn
Received: July 24, 2022
Peer-review started: July 24, 2022
First decision: August 22, 2022
Revised: September 13, 2022
Accepted: October 26, 2022
Article in press: October 26, 2022
Published online: November 26, 2022
Processing time: 121 Days and 22.2 Hours
Core Tip

Core Tip: Optic nerve sheath diameter (ONSD) and ONSD/eyeball transverse diameter (ETD) were correlated with intracranial pressure and prognosis. This study aimed to evaluate the roles of ONSD and ONSD/ETD ratio in predicting prognosis of death in comatose patients with acute stroke during hospitalization. Total 67 comatose patients were retrospectively recruited. ONSD and ETD were measured by cranial computed tomography scans within 24 h after coma onset. It was found that the mortality increased when ONSD > 5.7 mm or ONSD/ETD ratio > 0.25. The ONSD/ETD ratio was more stable than ONSD alone, which be preferred in clinical practice.