Retrospective Study
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Nov 6, 2022; 10(31): 11338-11348
Published online Nov 6, 2022. doi: 10.12998/wjcc.v10.i31.11338
Nomogram for predicting overall survival in Chinese triple-negative breast cancer patients after surgery
Wei-Xun Lin, Yan-Na Xie, Yao-Kun Chen, Jie-Hui Cai, Juan Zou, Jie-Hua Zheng, Yi-Yuan Liu, Zhi-Yang Li, Ye-Xi Chen
Wei-Xun Lin, Yao-Kun Chen, Jie-Hui Cai, Juan Zou, Jie-Hua Zheng, Yi-Yuan Liu, Zhi-Yang Li, Ye-Xi Chen, Department of Thyroid, Breast and Hernia Surgery, The Second Affiliated Hospital of Shantou University Medical College, Shantou 515041, Guangdong Province, China
Yan-Na Xie, Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Shantou University Medical College, Shantou 515041, Guangdong Province, China
Author contributions: Lin WL, Xie YN, Chen YX, Li ZY, Liu YY, and Cai JH designed the study and conceived the project; Zou J, Zheng JH, Chen YK, and Xie YN performed the experiments and analyzed the data; Lin WX and Xie YN drafted the manuscript; All authors have read and approved the manuscript.
Supported by the Special Fund Project of Guangdong Science and Technology, No. 210728156901524, and No. 210728156901519; Medical Scientific Research Foundation of Guangdong Province, China, No. A2021432, and No. B2021448; Shantou Medical Science and Technology Planning Project, No. 210521236491457, and No. 210625106490696.
Institutional review board statement: Not applicable, Patient data comes from the SEER*stat version 8.3.5.
Informed consent statement: Not applicable, Patient data comes from the SEER*stat version 8.3.5.
Conflict-of-interest statement: All the authors declare that they have no conflict of interest.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ye-Xi Chen, MD, Doctor, Department of Thyroid, Breast and Hernia Surgery, The Second Affiliated Hospital of Shantou University Medical College, No. 69 North Dongxia Road, Shantou 515041, China. yxchen3@stu.edu.cn
Received: September 12, 2021
Peer-review started: September 12, 2021
First decision: January 10, 2022
Revised: January 25, 2022
Accepted: August 6, 2022
Article in press: August 6, 2022
Published online: November 6, 2022
Processing time: 409 Days and 14.9 Hours
Core Tip

Core tip: This study aimed to construct and validate a nomogram for overall survival (OS) of triple-negative breast cancer (TNBC) patients after surgery. The data from SEER*stat 8.3.5 of selected Chinese surgical patients with TNBC between 2010 and 2015 were used. The multivariate analysis showed that age (P = 0.043), marital status (P = 0.040), tumor localization (P = 0.030), grade (P = 0.035), T classification (P = 0.012), and N classification (P = 0.002) were independent prognostic factors. A risk stratification model was generated. The C-indexes of the nomogram to predict OS were 0.766 and compared to the seventh edition tumor, node, metastasis (TNM) staging system, which was higher (0.766 vs 0.707, P < 0.001). The nomogram provided a clear prognostic superiority over the traditional TNM system.