Opinion Review
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jan 21, 2022; 10(3): 753-761
Published online Jan 21, 2022. doi: 10.12998/wjcc.v10.i3.753
Lung injury after cardiopulmonary bypass: Alternative treatment prospects
Xue-Mei Zheng, Zhuo Yang, Guang-Li Yang, Yan Huang, Jie-Ru Peng, Meng-Jun Wu
Xue-Mei Zheng, School of Medicine, University of Electronic Science and Technology of China, Chengdu 610000, Sichuan Province, China
Zhuo Yang, Department of Pharmacy, Chengdu Women’s and Children’s Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu 610000, Sichuan Province, China
Guang-Li Yang, Department of Medical Administration, Chengdu Women’s and Children’s Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu 610000, Sichuan Province, China
Yan Huang, National Institute of Drug Clinical Trial, Chengdu Women’s and Children’s Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu 610000, Sichuan Province, China
Jie-Ru Peng, Department of Medical Records Statistics, Chengdu Women’s and Children’s Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu 610000, Sichuan Province, China
Meng-Jun Wu, Department of Anesthesiology, The Affiliated Hospital, School of Medicine, Chengdu Women's and Children's Central Hospital, University of Electronic Science and Technology, Chengdu 610000, Sichuan Province, China
Author contributions: Zheng XM, Yang Z and Yang GL contributed equally to this work; Wu MJ designed the research study; Zheng XM, Yang Z collected data from the literature; Zheng XM, Yang Z, Peng JR, Huang Y and Yang GL wrote the manuscript; Wu MJ conducted a review of the manuscript; all authors have read and approve the final manuscript.
Conflict-of-interest statement: The authors have no potential conflicts of interest to disclose.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Meng-Jun Wu, MD, PhD, Associate Chief Physician, Department of Anesthesiology, The Affiliated Hospital, School of Medicine, Chengdu Women's and Children's Central Hospital, University of Electronic Science and Technology, No. 1617 Riyue Avenue, Qingyang District, Chengdu 610000, Sichuan Province, China. 3400164739@qq.com
Received: August 10, 2021
Peer-review started: August 10, 2021
First decision: October 20, 2021
Revised: October 29, 2021
Accepted: December 23, 2021
Article in press: December 23, 2021
Published online: January 21, 2022
Processing time: 158 Days and 1.8 Hours
Core Tip

Core Tip: Respiratory dysfunction is a well-recognized side effect of cardiac surgery combined with cardiopulmonary bypass (CPB). The mechanism of lung injury after CPB is unclear, and the lack of effective treatment results in poor prognosis. This review summarizes the mechanisms of lung injury and proposes a new treatment option.