Retrospective Study
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Oct 6, 2022; 10(28): 10077-10084
Published online Oct 6, 2022. doi: 10.12998/wjcc.v10.i28.10077
Endovascular treatment vs drug therapy alone in patients with mild ischemic stroke and large infarct cores
Wen-Hui Kou, Xiao-Qin Wang, Jin-Shui Yang, Nan Qiao, Xiao-Hui Nie, Ai-Mei Yu, Ai-Xia Song, Qian Xue
Wen-Hui Kou, Xiao-Qin Wang, Jin-Shui Yang, Nan Qiao, Xiao-Hui Nie, Ai-Mei Yu, Ai-Xia Song, Qian Xue, Department of Neurology, First Affiliated Hospital of Hebei North University, Zhangjiakou 075061, Hebei Province, China
Author contributions: Kou WH, Wang XQ, Yang JS, Qiao N, Nie XH, Yu AM, Song AX, and Xue Q designed the research study; Kou WH, Wang XQ, and Yang JS performed the research; and all authors have read and approved the final manuscript.
Supported by Scientific Research Fund of Hebei Health Commission 2022, No. 20220591.
Institutional review board statement: The study was reviewed and approved by the First Affiliated Hospital of Hebei North University Institutional Review Board.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: The authors declare no conflict of interest.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ai-Xia Song, MD, Associate Chief Physician, Department of Neurology, First Affiliated Hospital of Hebei North University, No. 12 Changqing Road, Zhangjiakou 075061, Hebei Province, China. 1979958315@qq.com
Received: June 12, 2022
Peer-review started: June 12, 2022
First decision: July 14, 2022
Revised: August 2, 2022
Accepted: August 22, 2022
Article in press: August 22, 2022
Published online: October 6, 2022
Processing time: 107 Days and 1.5 Hours
Core Tip

Core Tip: Fast and correct first aid can save lives and avoid disabilities in patients with acute ischemic stroke. The limited therapeutic time window and relative contraindications confine medical care for the treatment of acute ischemic stroke. Endovascular therapy ranks among the major therapies from an important alternative for medical therapy in the treatment of acute ischemic stroke. The present study compared the clinical efficacy and safety of these two treatment approaches in patients with acute ischemic stroke. It found that the two approaches achieved comparable results in favorable prognosis. However, endovascular therapy can effectively improve neurological function compared with medical therapy.