Case Report
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Sep 6, 2022; 10(25): 9087-9095
Published online Sep 6, 2022. doi: 10.12998/wjcc.v10.i25.9087
Renal cell carcinoma presented with a rare case of icteric Stauffer syndrome: A case report
Dimitar R Popov, Krasimir A Antonov, Evelina G Atanasova, Christo P Pentchev, Lyuben M Milatchkov, Maria D Petkova, Krasimir G Neykov, Rosen K Nikolov
Dimitar R Popov, Krasimir A Antonov, Christo P Pentchev, Maria D Petkova, Rosen K Nikolov, Medical University of Sofia, Sofia 1431, Bulgaria
Dimitar R Popov, Krasimir A Antonov, Evelina G Atanasova, Christo P Pentchev, Lyuben M Milatchkov, Maria D Petkova, Rosen K Nikolov, Clinic of Gastroenterology, University Hospital ’St. Ivan Rilski’, Sofia 1431, Bulgaria
Krasimir G Neykov, Clinic of Urology, National Oncology Hospital, Sofia 1756, Bulgaria
Author contributions: Popov DR, Antonov KA, and Nikolov RK conceived and supervised the study; Atanasova EG, Pentchev CP, Milatchkov LM, and Petkova MD collected the clinical data and followed up with the patient; Popov DR and Antonov KA analyzed the data; Neykov KG contributed to the nephrectomy procedures; Pentchev CP, Atanasova EG, Milatchkov LM, and Petkova MD wrote the paper; all authors have read and approved the final manuscript.
Informed consent statement: The authors declare that the person involved in the case report gave his informed consent to be involved in the study. The informed consent has been provided to the publisher.
Conflict-of-interest statement: The authors declare that there are no conflicts of interest associated with this work.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Evelina G Atanasova, MD, PhD, Staff Physician, Clinic of Gastroenterology, University Hospital ‘St. Ivan Rilski’, ‘Akademik Ivan Evstratiev Geshov’ Blvd. No. 15, Sofia 1431, Bulgaria. eva_gatanasova@abv.bg
Received: April 2, 2022
Peer-review started: April 2, 2022
First decision: May 31, 2022
Revised: June 16, 2022
Accepted: August 1, 2022
Article in press: August 1, 2022
Published online: September 6, 2022
Processing time: 145 Days and 14.6 Hours
Core Tip

Core Tip: Initial presentation of jaundice, in cases of non-hepatic malignancy, is generally associated with metastatic liver disease. Despite the increased bilirubin levels, surgical treatment, when possible, is an appropriate approach in a case with non-metastatic cholestatic syndrome. Stauffer syndrome is a rare presentation of kidney and urinary tract malignancies and even rarer when presented with jaundice.