Case Report
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Aug 16, 2022; 10(23): 8277-8283
Published online Aug 16, 2022. doi: 10.12998/wjcc.v10.i23.8277
Complete resection of large-cell neuroendocrine and hepatocellular carcinoma of the liver: A case report
Byeong Gwan Noh, Hyung-Il Seo, Young Mok Park, Suk Kim, Seung Baek Hong, So Jeong Lee
Byeong Gwan Noh, Hyung-Il Seo, Young Mok Park, Division of HBP Surgery and Transplantation, Department of Surgery, Pusan National University School of Medicine, Biomedical Research Institute, Pusan National University Hospital, Busan 49241, South Korea
Suk Kim, Seung Baek Hong, Department of Radiology, Pusan National University School of Medicine, Biomedical Research Institute, Pusan National University Hospital, Busan 49241, South Korea
So Jeong Lee, Department of Pathology, Pusan National University School of Medicine, Biomedical Research Institute, Pusan National University Hospital, Busan 49241, South Korea
Author contributions: All authors contributed to the acquisition of data for this study; Noh BG analyzed the data and wrote the draft manuscript; Seo HI designed the research study; Park YM contributed to the data analysis; Noh BG, Park YM, Seo HI, Kim S, Hong SB, and Lee SJ performed the research; all authors have read and approved the final manuscript.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: All authors report no relevant conflict of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hyung-Il Seo, PhD, Professor, Division of HBP Surgery and Transplantation, Department of Surgery, Pusan National University School of Medicine, Biomedical Research Institute, Pusan National University Hospital, 179 Gudeok-ro, Seo-gu, Busan 49241, South Korea. seohi71@hanmail.net
Received: February 16, 2022
Peer-review started: February 16, 2022
First decision: May 30, 2022
Revised: June 5, 2022
Accepted: July 11, 2022
Article in press: July 11, 2022
Published online: August 16, 2022
Processing time: 165 Days and 22.4 Hours
Core Tip

Core Tip: Collision tumors originating from the liver are extremely rare. No rational surgical strategies for these tumors have been reported because of their rarity, the shortness of knowledge of predictive prognostic factors, the inability to identify progression, and the limited understanding of the biohistology of these lesions. However, complete resection of a resectable locoregional neuroendocrine tumor has excellent outcomes. Because of their rarity, there are no proper guidelines for adjuvant treatment. It is necessary to discuss each clinical experience and consider an appropriate method for the preoperative diagnosis and treatment.