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©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Aug 16, 2022; 10(23): 8124-8132
Published online Aug 16, 2022. doi: 10.12998/wjcc.v10.i23.8124
Published online Aug 16, 2022. doi: 10.12998/wjcc.v10.i23.8124
Distinctive clinical features of spontaneous pneumoperitoneum in neonates: A retrospective analysis
Soo-Hong Kim, Yong-Hoon Cho, Hae-Young Kim, Department of Surgery, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Yangsan 50612, South Korea
Yong-Hoon Cho, Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan 50612, South Korea
Author contributions: Cho YH and Kim SH contributed to study conception and design, drafting and revision of the manuscript, and finalization of the submission; Kim HY contributed to data analysis and interpretation; All authors reviewed the final manuscript.
Supported by A 2-Year Research Grant of Pusan National University , No. 201812270003 .
Institutional review board statement: This study was reviewed and approved by the Pusan National University Yangsan Hospital Institutional Review Board also approved to progress this project without informed consent, No. 05-2020-044.
Informed consent statement: This study is a retrospective cohort study. Therefore, it was impossible to get consent from patients and their guardians in advance. This study was not for research purpose about human subject itself, so it does not contain any concerned data. It may be published as a journal worthy of being open in public after collecting data of managements for the past 12 years. Moreover, Pusan National University Yangsan Hospital Institutional Review Board also approved to carry out this project without informed consent
Conflict-of-interest statement: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Data sharing statement: No additional data are available. All data relevant to the study are included in the article and are also available upon reasonable request.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yong-Hoon Cho, MD, Professor, Department of Surgery, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Geumo-ro 20, Mulgeumeup, Yangsan 50612, South Korea. choyh70@pusan.ac.kr
Received: December 17, 2021
Peer-review started: December 17, 2021
First decision: February 21, 2022
Revised: March 2, 2022
Accepted: June 30, 2022
Article in press: June, 30, 2022
Published online: August 16, 2022
Processing time: 227 Days and 2.5 Hours
Peer-review started: December 17, 2021
First decision: February 21, 2022
Revised: March 2, 2022
Accepted: June 30, 2022
Article in press: June, 30, 2022
Published online: August 16, 2022
Processing time: 227 Days and 2.5 Hours
Core Tip
Core Tip: This study shows a higher mortality rate in a spontaneous pneumoperitoneum (SP) group than pneumoperitoneum secondary to gastrointestinal perforation, contrary to previous studies. Additionally, neonates with SP were more likely to have thrombocytopenia and accompany pneumothorax and persistent pulmonary hypertension. Preterm infants were the most significant factor affecting its mortality. These distinctive clinical features should be considered in the management of SP.