Case Report
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jul 26, 2022; 10(21): 7553-7564
Published online Jul 26, 2022. doi: 10.12998/wjcc.v10.i21.7553
Chronic urticaria associated with lung adenocarcinoma — a paraneoplastic manifestation: A case report and literature review
Luisa Fernanda Jiménez, Evis Adriana Castellón, Juan David Marenco, José Maria Mejía, Camilo Andrés Rojas, Franklin Torres Jiménez, Linda Coronell, Estefanie Osorio-Llanes, Evelyn Mendoza-Torres
Luisa Fernanda Jiménez, Evis Adriana Castellón, Juan David Marenco, José Maria Mejía, Camilo Andrés Rojas, Franklin Torres Jiménez, Linda Coronell, Faculty of Health Sciences, Universidad Libre de Colombia, Seccional Barranquilla, Barranquilla 08000, Colombia
Estefanie Osorio-Llanes, Faculty of Exact and Natural Sciences, Universidad Libre de Colombia, Seccional Barranquilla, Barranquilla 08000, Colombia
Evelyn Mendoza-Torres, Faculty of Health Sciences, Universidad Libre De Colombia, Seccional Barranquilla, Barranquilla 08000, Atlántico, Colombia
Author contributions: All authors participated in writing the manuscript and approving the final version.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors have no conflicts of interest to declare.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Evelyn Mendoza-Torres, MSc, PhD, Adjunct Associate Professor, Health Science Faculty, Universidad Libre De Colombia, Seccional Barranquilla, Km 7 Vía a Puerto Colombia, Barranquilla 08000, Atlántico, Colombia. evelyn.mendozat@unilibre.edu.co
Received: February 11, 2022
Peer-review started: February 11, 2022
First decision: March 23, 2022
Revised: April 7, 2022
Accepted: June 4, 2022
Article in press: June 4, 2022
Published online: July 26, 2022
Processing time: 149 Days and 12 Hours
Core Tip

Core Tip: This case of urticaria associated with adenocarcinoma highlights the histopathological report where the thyroid transcription factor 1 (TTF-1) was highly expressed by the lung tissue and its relationship with lung cancer. TTF-1 regulates the transcription of specific genes in the thyroid, lung, and diencephalon. This transcription factor is also known as a thyroid-specific enhancer-binding protein and is used in pathology as a marker to determine whether a tumor arises from the lung or thyroid.