Case Control Study
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jan 14, 2022; 10(2): 426-436
Published online Jan 14, 2022. doi: 10.12998/wjcc.v10.i2.426
Methylprednisolone accelerate chest computed tomography absorption in COVID-19: A three-centered retrospective case control study from China
Lan Lin, Dan Xue, Jin-Hua Chen, Qiong-Ying Wei, Zheng-Hui Huang
Lan Lin, Dan Xue, Qiong-Ying Wei, Zheng-Hui Huang, Department of Respiratory Medicine, Fujian Medical University Union Hospital, Fuzhou 350001, Fujian Province, China
Jin-Hua Chen, Department of Medical Administration, Fujian Medical University Union Hospital, Fuzhou 350001, Fujian Province, China
Author contributions: Lin L and Huang ZH designed the study and drafted the manuscript; Lin L, Xue D, Wei QY and Huang ZH were responsible for the clinical treatment of patients and conducted the acquisition of clinical data; Chen JH conducted the acquisition, analysis and interpretation of data; Chen JH and Huang ZH revised the manuscript for relevant important intellectual content; all authors have read and approved the final version of the manuscript.
Supported by the Fujian Medical University COVID-19 Prevention and Treatment Research Contingency Key Project, No. 2020YJ006; the Science and Technology Program Guided Projects, Fujian Province, China, No. 2020Y0036.
Institutional review board statement: The study was reviewed and approved by the Medical Ethics Committee of Fujian Medical University Union Hospital Institutional Review Board (No. 2020KJTXGF001).
Informed consent statement: Patients signed an informed consent.
Conflict-of-interest statement: The authors have no conflicts of interest.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Zheng-Hui Huang, MD, Associate Chief Physician, Department of Respiratory Medicine, Fujian Medical University Union Hospital, No. 29 Xinquan Road, Gulou District, Fuzhou 350001, Fujian Province, China. 13665028181@163.com
Received: August 17, 2021
Peer-review started: August 17, 2021
First decision: November 3, 2021
Revised: November 12, 2021
Accepted: December 2, 2021
Article in press: December 2, 2021
Published online: January 14, 2022
Processing time: 147 Days and 15.6 Hours
Core Tip

Core Tip: This study aimed to explore the efficacy and safety of methylprednisolone for treating coronavirus disease 2019 (COVID-19). Low-to-moderate dose short-term methylprednisolone could accelerate the chest computed tomography imaging absorption of COVID-19 and prevent it from deteriorating into critical type, shorten hospital stay and save medical resources.