Case Report
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World J Clin Cases. Jun 26, 2022; 10(18): 6283-6288
Published online Jun 26, 2022. doi: 10.12998/wjcc.v10.i18.6283
Coinfection of Streptococcus suis and Nocardia asiatica in the human central nervous system: A case report
Ying-Ying Chen, Xin-Hong Xue
Ying-Ying Chen, Xin-Hong Xue, Department of Neurology, Liaocheng People’s Hospital, Liaocheng 252000, Shandong Province, China
Author contributions: Chen YY reviewed the literature, analyzed the patient data and wrote the manuscript; Xue XH and Chen YY were responsible for data collection; All the authors read and approved the final manuscript.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflicts of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Corresponding author: Xin-Hong Xue, Doctor, Additional Professor, Department of Neurology, Liaocheng People’s Hospital, No. 67, Dongchang West Road, Liaocheng 252000, Shandong Province, China.
Received: December 17, 2021
Peer-review started: December 17, 2021
First decision: January 18, 2022
Revised: February 19, 2022
Accepted: April 21, 2022
Article in press: April 21, 2022
Published online: June 26, 2022
Core Tip

Core Tip: Streptococcus suis (S. suis) meningitis is rare in the neurology department. S. suis combined with Nocardia is also rare, and intracranial infection of atypical pathogens is difficult to identify. Streptococcus cultivation requires high nutrition. In addition, the difficulty of cultivating S. suis makes the clinical identification more challenging and usually prolongs therapies. mNGS can be utilized to determine pathogens in the early phase of illness.