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World J Clin Cases. Jun 26, 2022; 10(18): 5946-5956
Published online Jun 26, 2022. doi: 10.12998/wjcc.v10.i18.5946
Strategies and challenges in treatment of varicose veins and venous insufficiency
Rong-Ding Gao, Song-Yi Qian, Hai-Hong Wang, Yong-Sheng Liu, Shi-Yan Ren
Rong-Ding Gao, Shi-Yan Ren, Department of Laser and Vascular Surgery, Aviation General Hospital, China Medical University, Beijing 100012, China
Song-Yi Qian, Department of Cardiac Surgery, Zhongshan Hospital (Xiamen Brach), Fudan University, Xiamen 361015, Fujian Province, China
Hai-Hong Wang, Department of Peripheral Vascular Disease, The Affiliated Hospital of Shanxi University of Chinese Medicine, Taiyuan 030024, Shanxi Province, China
Yong-Sheng Liu, Department of Dermatology, Aviation General Hospital, China Medical University, Beijing 100012, China
Author contributions: Qian SY and Gao RD contributed equally to this manuscript by composing the manuscript; Ren SY searched and studied the references and designed, wrote, revised, and submitted the manuscript; Wang HH and Liu YS discussed the manuscript; all authors have read and approved the final manuscript.
Conflict-of-interest statement: No conflict of interest exists.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Shi-Yan Ren, MD, PhD, Chief Doctor, Vascular Surgeon, Department of Laser and Vascular Surgery, Aviation General Hospital, China Medical University, No. 2 Beiyuan Road, Chaoyang District, Beijing 100012, China. rens66@126.com
Received: December 3, 2021
Peer-review started: December 3, 2021
First decision: March 15, 2022
Revised: March 26, 2022
Accepted: April 26, 2022
Article in press: April 26, 2022
Published online: June 26, 2022
Processing time: 195 Days and 14.6 Hours
Core Tip

Core Tip: Endovenous laser ablation (EVLA) is the most cost-effective therapeutic option, with radiofrequency ablation (RFA) being a close second for the treatment of patients with varicose veins. Endovenous thermal ablation (EVLA or RFA) is recommended as a first-line treatment for varicose veins and has substituted the high ligation of saphenofemoral junctional reflux and stripping of varicose veins. In terms of recurrence of varicose veins, there is little or no difference between Cure conservatrice et Hemodynamique de l'Insufficience Veineuse en Ambulatoire and EVLA, RFA, or stripping. Ultrasound guided foam sclerotherapy is associated with a high recurrence rate and can be used in conjunction with other procedures. Mechanochemical endovenous ablation and cyanoacrylate embolization appear promising, but evidence on their effectiveness is warranted.