Case Report
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. May 6, 2022; 10(13): 4145-4152
Published online May 6, 2022. doi: 10.12998/wjcc.v10.i13.4145
Primitive neuroectodermal tumor of the prostate in a 58-year-old man: A case report
Da-Wei Tian, Xiao-Chun Wang, Hui Zhang, Yan Tan
Da-Wei Tian, College of Medical Imaging, Shanxi Medical University, Taiyuan 030001, Shanxi Province, China
Xiao-Chun Wang, Hui Zhang, Yan Tan, Department of Radiology, The First Hospital of Shanxi Medical University, Taiyuan 030001, Shanxi Province, China
Author contributions: Tian DW reviewed the literature and contributed to manuscript drafting; Wang XC interpreted the imaging findings and contributed to manuscript drafting; Zhang H and Tan Y revised the manuscript.
Supported by National Natural Science Foundation of China, Nos. 81971593, 81771824, 81971592, and 82071893; and Fund Program for the Scientific Activities of Selected Returned Overseas Professionals in Shanxi Province, No. 20200003.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest to disclose.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yan Tan, MD, Professor, Department of Radiology, The First Hospital of Shanxi Medical University, No. 85 Jiefang South Road, Taiyuan 030001, Shanxi Province, China. tanyan123456@sina.com
Received: July 30, 2021
Peer-review started: July 30, 2021
First decision: October 25, 2021
Revised: November 2, 2021
Accepted: March 14, 2022
Article in press: March 14, 2022
Published online: May 6, 2022
Processing time: 273 Days and 15.2 Hours
Core Tip

Core Tip: Prostatic primitive neuroectodermal tumors (PNETs) are usually malignant and occur in young men (median age: 29 years; range: 20 to 58 years) with predominant complaints of dysuria, often with normal prostate specific antigen levels. Prostatic PNETs may invade adjacent organs, including the bladder, rectum, and seminal vesicles, and are prone to distant metastases. Forty-four percent of patients develop metastases, most commonly (75%) in the lung. CD99 is the most accepted immunohistochemical marker for prostatic PNETs. Almost all patients receive chemotherapy. Despite combination therapy, including surgery, chemotherapy, and radiotherapy, the median survival of the patients remains unsatisfactory at 13 mo.