Case Report
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Apr 6, 2022; 10(10): 3297-3305
Published online Apr 6, 2022. doi: 10.12998/wjcc.v10.i10.3297
Dedifferentiated chondrosarcoma of the middle finger arising from a solitary enchondroma: A case report
Hirotaka Yonezawa, Norio Yamamoto, Katsuhiro Hayashi, Akihiko Takeuchi, Shinji Miwa, Kentaro Igarashi, Sei Morinaga, Yohei Asano, Shiro Saito, Yasunori Tome, Hiroko Ikeda, Takayuki Nojima, Hiroyuki Tsuchiya
Hirotaka Yonezawa, Norio Yamamoto, Katsuhiro Hayashi, Akihiko Takeuchi, Shinji Miwa, Kentaro Igarashi, Sei Morinaga, Yohei Asano, Shiro Saito, Takayuki Nojima, Hiroyuki Tsuchiya, Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa 920-8641, Ishikawa, Japan
Yasunori Tome, Department of Orthopedic Surgery, Graduate School of Medicine, University of the Ryukyus, Nishihara 903-0215, Okinawa, Japan
Hiroko Ikeda, Takayuki Nojima, Department of Diagnostic Pathology, Kanazawa University Hospital, Kanazawa 920-8641, Ishikawa, Japan
Author contributions: Tsuchiya H, Tome Y and Yonezawa H served as the patient’s surgeons, reviewed the literature and contributed to manuscript drafting; Ikeda H and Nojima T reviewed the pathological findings and contributed to manuscript drafting; Yamamoto N, Hayashi K, Takeuchi A and Miwa S analyzed and interpreted the imaging findings; Igarashi K, Morinaga S, Asano Y and Saito S were responsible for the revision of the manuscript for important intellectual content; all authors issued final approval for the version to be submitted.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Norio Yamamoto, MD, PhD, Professor, Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, 13-1 Takara-machi, Kanazawa 920-8641, Ishikawa, Japan. norinori@med.kanazawa-u.ac.jp
Received: November 15, 2021
Peer-review started: November 15, 2021
First decision: January 11, 2022
Revised: January 19, 2022
Accepted: February 20, 2022
Article in press: February 20, 2022
Published online: April 6, 2022
Processing time: 133 Days and 22.7 Hours
Core Tip

Core Tip: Dedifferentiated chondrosarcoma (DDCS) is a very rare primary malignant bone tumor. Furthermore, malignant transformation of a single enchondroma of the hand bone into DDCS is considered extremely rare, with no detail of precursor pathological findings being reported previously. There have been no reports showing preexisting enchondromas prior to wide resection. Our report evaluated the histological findings of a precursor lesion, and the specimen showed a typical benign enchondroma, suggesting that DDCS can arise from enchondroma.