Lin ZZ, Chen D, Liu S, Yu JH, Liu SR, Zhu ML. Mycobacterium tuberculosis bacteremia in a human immunodeficiency virus-negative patient with liver cirrhosis: A case report. World J Clin Cases 2022; 10(10): 3284-3290 [PMID: 35647124 DOI: 10.12998/wjcc.v10.i10.3284]
Corresponding Author of This Article
Ming-Li Zhu, MMed, Chief Technician, Department of Open Laboratory Medicine, Hangzhou Xixi Hospital Affiliated to Zhejiang Chinese Medical University, No. 2 Hengbu Street, Hangzhou 310000, Zhejiang Province, China. mlzhhz@163.com
Research Domain of This Article
Microbiology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Apr 6, 2022; 10(10): 3284-3290 Published online Apr 6, 2022. doi: 10.12998/wjcc.v10.i10.3284
Mycobacterium tuberculosis bacteremia in a human immunodeficiency virus-negative patient with liver cirrhosis: A case report
Zhe-Zhe Lin, Dan Chen, Sai Liu, Jian-Hua Yu, Shou-Rong Liu, Ming-Li Zhu
Zhe-Zhe Lin, Dan Chen, Sai Liu, Ming-Li Zhu, Department of Open Laboratory Medicine, Hangzhou Xixi Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou 310000, Zhejiang Province, China
Jian-Hua Yu, Department of Infectious Diseases, Hangzhou Xixi Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou 310000, Zhejiang Province, China
Shou-Rong Liu, Department of Hepatology, Hangzhou Xixi Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou 310000, Zhejiang Province, China
Author contributions: Lin ZZ and Chen D reviewed the literature and contributed to the manuscript draft; Liu S carried out the pathological analysis and interpretation; Yu JH and Liu SR analyzed and interpreted the image data; Zhu ML revised the manuscript for important intellectual content; all authors approved the final manuscript for submission.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and all accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ming-Li Zhu, MMed, Chief Technician, Department of Open Laboratory Medicine, Hangzhou Xixi Hospital Affiliated to Zhejiang Chinese Medical University, No. 2 Hengbu Street, Hangzhou 310000, Zhejiang Province, China. mlzhhz@163.com
Received: November 23, 2021 Peer-review started: November 23, 2021 First decision: January 11, 2022 Revised: February 4, 2022 Accepted: February 23, 2022 Article in press: February 23, 2022 Published online: April 6, 2022 Processing time: 125 Days and 21.2 Hours
Core Tip
Core Tip: Our findings are interesting in two ways. First, although Mycobacterium tuberculosis (M. tuberculosis) bacteremia is a common occurrence in acquired immunodeficiency syndrome patients, it has rarely been reported from human immunodeficiency virus (HIV)-negative patients. We report here, however, a case of M. tuberculosis bacteremia in an HIV-negative patient diagnosed with liver cirrhosis. This finding should alert physicians to consider the possibility of M. tuberculosis bacteremia in patient populations not usually considered to be vulnerable to such infections. Second, our successful use of next-generation sequencing for detection of M. tuberculosis in the blood should be of interest to physicians as a tool for early detection of microbial infection.
