Case Control Study
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Apr 6, 2022; 10(10): 3027-3034
Published online Apr 6, 2022. doi: 10.12998/wjcc.v10.i10.3027
Combined sevoflurane-dexmedetomidine and nerve blockade on post-surgical serum oxidative stress biomarker levels in thyroid cancer patients
Dan Du, Qiao Qiao, Zheng Guan, Yan-Feng Gao, Qiang Wang
Dan Du, Qiao Qiao, Zheng Guan, Yan-Feng Gao, Qiang Wang, Department of Anesthesiology, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an 710061, Shaanxi Province, China
Author contributions: Du D and Wang Q designed the study; Qiao Q, Guan Z and Gao YF collected the data; Du D and Qiao Q analyzed and interpreted the data; Du D wrote the article.
Supported by Clinical Research Award of the First Affiliated Hospital of Xi’an Jiaotong University, China, No. XJTU1AF-CRF-2017-009.
Institutional review board statement: This study was approved by The First Affiliated Hospital of Xi’an Jiaotong University Ethics Committee.
Informed consent statement: All study participants provided informed consent prior to study enrollment.
Conflict-of-interest statement: The authors declare that there is no conflict of interest to disclose.
Data sharing statement: All data relevant to the study have been included in the paper.
STROBE statement: The authors have read the STROBE Statement - checklist of items, and the manuscript was prepared and revised according to the STROBE Statement - checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Qiang Wang, MD, Chief Physician, Department of Anesthesiology, The First Affiliated Hospital of Xi’an Jiaotong University, No. 277 West Yanta Road, Xi’an 710061, Shaanxi Province, China. wang_qiangwq183@163.com
Received: December 5, 2021
Peer-review started: December 5, 2021
First decision: January 10, 2022
Revised: February 6, 2022
Accepted: February 23, 2022
Article in press: February 23, 2022
Published online: April 6, 2022
Processing time: 114 Days and 1.8 Hours
Core Tip

Core Tip: We recruited 96 thyroid cancer patients admitted to hospital between January 2019 and December 2020. Patients were divided into the control (47 cases) and experimental (49 cases) groups. Sevoflurane-dexmedetomidine inhalation general anesthesia combined with cervical plexus nerve block can reduce the postoperative stress and inflammatory responses in patients with thyroid cancer, while maintaining high anesthesia effectiveness and safety.