Case Report
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jan 7, 2022; 10(1): 361-370
Published online Jan 7, 2022. doi: 10.12998/wjcc.v10.i1.361
Diagnostic and surgical challenges of progressive neck and upper back painless masses in Madelung’s disease: A case report and review of literature
Ya-Jie Yan, Shi-Qing Zhou, Chun-Qiao Li, Yan Ruan
Ya-Jie Yan, Chun-Qiao Li, Yan Ruan, Department of Otorhinolaryngology, the First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, Guangdong Province, China
Shi-Qing Zhou, Department of Experimental Research, State Key Laboratory of Oncology in South China, Sun Yat-sen University Cancer Center, Guangzhou 510075, Guangdong Province, China
Shi-Qing Zhou, Department of Otorhinolaryngology head and neck, the Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510120, Guangdong Province, China
Author contributions: Yan YJ collected the clinical data, discussed the details, and contributed to writing the manuscript; Zhou SQ and Ruan Y contributed to the follow-up of the patient and modified the manuscript; Li CQ modified the manuscript and was a major contributor to writing the manuscript.
Supported by the National Natural Science Foundation of China, No. 81974581; Basic and Applied Research Foundation of Guangdong Province, China, No. 2020A1515110407; Scientific Research Fund of Guangdong Provincial Bureau of Traditional Chinese Medicine China, No. 20211200.
Informed consent statement: Written informed consent was obtained from the patient for the publication of this report and any accompanying images.
Conflict-of-interest statement: The authors have no conflicts of interest to disclose.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised accordingly.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Chun-Qiao Li, MD, Attending Doctor, Department of Otorhinolaryngology, the First Affiliated Hospital of Guangzhou University of Chinese Medicine, No. 16 Jichang Road, Baiyun District, Guangzhou 510405, Guangdong Province, China. lichunqiao18154920@163.com
Received: August 19, 2021
Peer-review started: August 19, 2021
First decision: November 1, 2021
Revised: November 14, 2021
Accepted: December 3, 2021
Article in press: December 3, 2021
Published online: January 7, 2022
Processing time: 132 Days and 20.7 Hours
Core Tip

Core Tip: Madelung’s disease (MD) is a rare chronic alcoholism-associated metabolic syndrome characterized by symmetrical deposition of adipose tissue subcutaneously in the head, neck, shoulders, back, trunk, and nerve roots of the upper and lower limbs. No consensus exists concerning the diagnosis, pathogenesis, and treatment of MD. Recently, a patient with MD accompanied by hypertension had undergone surgical resection and recovered well at our hospital. Herein, we present this case to improve clinicians’ diagnosis and treatment of MD while emphasizing the manifestations of MD presenting as head and neck masses.