Chen JY, Cen B, Hu F, Qiu Y, Xiao GM, Zhou JG, Zhang FC. Clinical characteristics and outcomes of primary intracranial alveolar soft-part sarcoma: A case report. World J Clin Cases 2022; 10(1): 296-303 [PMID: 35071531 DOI: 10.12998/wjcc.v10.i1.296]
Corresponding Author of This Article
Fang-Cheng Zhang, MD, Professor, Department of Neurosurgery, Wuhan Union Hospital, No. 1277 Jiefang Avenue, Wuhan 430010, Hubei Province, China. zfcwhuh@gmail.com
Research Domain of This Article
Oncology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Jun-Yu Chen, Bo Cen, Fei Hu, Yong Qiu, Guo-Min Xiao, Jun-Ge Zhou, Department of Neurosurgery, General Hospital of the Yangtze River Shipping, Wuhan 430010, Hubei Province, China
Fang-Cheng Zhang, Department of Neurosurgery, Wuhan Union Hospital, Wuhan 430010, Hubei Province, China
Author contributions: Chen JY contributed to data curation, formal analysis, and original draft; Chen JY and Zhang FC contributed to conceptualization and methodology; Chen JY, Cen B, Qiu Y, and Zhou JG provided resources; Chen JY, Qiu Y, Xiao GM, and Zhang FC wrote the paper; Cen B and Zhou JG generated the figures/table for data visualization; Cen B and Hu F supervised the study; Fei Hu and Xiao GM validated the findings; Qiu Y, Xiao GM, and Zhang FC reviewed and edited paper.
Informed consent statement: Informed consent was obtained from all individual participants included in the study.
Conflict-of-interest statement: Authors have nothing to disclose.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Fang-Cheng Zhang, MD, Professor, Department of Neurosurgery, Wuhan Union Hospital, No. 1277 Jiefang Avenue, Wuhan 430010, Hubei Province, China. zfcwhuh@gmail.com
Received: May 18, 2021 Peer-review started: May 18, 2021 First decision: July 5, 2021 Revised: July 15, 2021 Accepted: November 30, 2021 Article in press: November 30, 2021 Published online: January 7, 2022 Processing time: 225 Days and 22.9 Hours
Core Tip
Core Tip: Alveolar soft part sarcoma, or alveolar soft-part sarcoma (ASPS), is reportedly a rare tumor with a high recurrent rate. Current understanding of primary intracranial ASPS, or primary intracranial ASPS (PIASPS), is limited to case reports or small case series that preclude statistical analysis of outcomes (e.g., progression-free survival or overall survival). In this article, we first reported 5 consecutive cases from our institute. Then, the 9 cases from previous studies were pooled and analyzed to delineate the characteristics of this disease. We found PIASPS was a rare malignancy and predominately affected young females. Patients with PIASPS suffer from poor outcomes, characterized by a high tendency of recurrence. Surgical treatment is the first choice and gross total resection should be achieved when the tumor is feasible. Besides, PIASPS benefit from radiotherapy, which should be considered as a part of treatment therapies.
