Published online Jul 16, 2013. doi: 10.12998/wjcc.v1.i4.149
Revised: May 31, 2013
Accepted: June 8, 2013
Published online: July 16, 2013
Core tip: Granular cell tumors are rare, usually benign, soft tissue tumors of neural origin. They can occur anywhere in the body with up to 15% situated in the vulva. Malignancy has been reported in about 2% of cases. We report a woman with a granular cell tumor of the vulva who underwent tumor excision but with focal extension to the resection margin on microscopy. Recurrence rates are 2%-8% with clear margins and 20% with positive margins. We conclude that intraoperative assessment by frozen section is advisable such that further excision can be performed for positive margins.