Retrospective Cohort Study
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Dec 16, 2021; 9(35): 10828-10837
Published online Dec 16, 2021. doi: 10.12998/wjcc.v9.i35.10828
Application of MAGnetic resonance imaging compilation in acute ischemic stroke
Qi Wang, Gang Wang, Qiang Sun, Di-He Sun
Qi Wang, Gang Wang, Qiang Sun, Di-He Sun, Department of Radiology, The Stroke Hospital of Liaoning Province, Shenyang 110101, Liaoning Province, China
Author contributions: Wang Q and Wang G designed and coordinated the study; Sun Q and Sun HD treated the patients.
Supported by Wu Jieping Medical Foundation, No. 320.6750.2020-11-22.
Institutional review board statement: The study was reviewed and approved for publication by our Institutional Reviewer.
Informed consent statement: All study participants or their legal guardian provided informed written consent about personal and medical data collection before study enrollment.
Conflict-of-interest statement: All the authors have no conflict of interest related to the manuscript.
Data sharing statement: No additional data are available.
STROBE statement: The authors have read the STROBE Statement checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Gang Wang, MD, Doctor, Department of Radiology, The Stroke Hospital of Liaoning Province, No. 49 Xuesong Road, Sujiatun District, Shenyang 110101, Liaoning Province, China. 444966958@qq.com
Received: July 23, 2021
Peer-review started: July 23, 2021
First decision: August 19, 2021
Revised: August 31, 2021
Accepted: October 20, 2021
Article in press: October 20, 2021
Published online: December 16, 2021
Processing time: 140 Days and 3.2 Hours
ARTICLE HIGHLIGHTS
Research background

Synthetic magnetic resonance imaging (MRI) MAGnetic resonance imaging compilation (MAGiC) is a new MRI technology. While completing one scan, the technician can acquire conventional T1, T2, T2-fluid-attenuated inversion recovery (FLAIR), and other contrast images, quantitative T1 mapping and T2 mapping images, as well as MAGiC phase-sensitive inversion recovery (PSIR) Vessel cerebrovascular images simultaneously through post-processing, which significantly shortens the scanning time required for MRI examination.

Research motivation

This study evaluated the application value of vascular images obtained by synthetic MRI in diagnosing acute ischemic stroke.

Research objectives

We hypothesized that the synthetic MRI vascular screening scheme can evaluate the degree of cerebral artery stenosis in patients with acute ischemic stroke.

Research methods

The contrast-to-noise ratio (CNR) values of traditional T1, T2, and T2-FLAIR images and MAGiC reconstructed T1, T2, and T2-FLAIR images in DWI diffusion restriction areas were measured and compared. MAGiC PSIR Vessel and time-of-flight magnetic resonance angiography (TOF MRA) images were used to measure and calculate the stenosis degree of bilateral middle cerebral artery stenosis areas. The consistency of MAGiC PSIR Vessel and TOF MRA in displaying the degree of vascular stenosis with computed tomography angiography was compared.

Research results

Magnetic resonance imaging can provide important imaging evidence in the prevention, diagnosis, and treatment of cerebrovascular diseases. However, its long scanning time, especially in patients with hyperacute stroke, contradicts the clinical need to carry out treatment as soon as possible. MAGiC PSIR Vessel images are generated simultaneously with conventional T1, T2, and other contrast images, as well as T1 mapping, T2 mapping, and other quantitative images, which can be initially used for screening intracranial blood vessels without occupying additional scanning time.

Research conclusions

MAGiC can simultaneously obtain a variety of conventional contrast images (T1, T2, T2-FLAIR, etc.), intracranial vessel images (MAGiC PSIR Vessel), and both T2 and T1 relaxation time quantitative images (T2 mapping, T1 mapping) in one scan, which can accurately determine the onset time of stroke, preliminarily screen intracranial vessels, and further shorten the magnetic resonance imaging examination time in patients with acute stroke.

Research perspectives

The evaluation of long-term outcomes of patients can further clarify the relationships of vascular stenosis degree judgment with cerebrovascular recanalization treatment and stroke recurrence.