Yeh KL, Wu SH, Liaw CK, Hou SM, Wu SS. Outcomes of different minimally invasive surgical treatments for vertebral compression fractures: An observational study. World J Clin Cases 2021; 9(31): 9509-9519 [PMID: 34877285 DOI: 10.12998/wjcc.v9.i31.9509]
Corresponding Author of This Article
Shing-Sheng Wu, MSc, Professor, Department of Orthopedics, Shin Kong Wu Ho-Su Memorial Hospital, No. 95 Wenchang Road, Shilin District, Taipei 11101, Taiwan. raysswu@gmail.com
Research Domain of This Article
Orthopedics
Article-Type of This Article
Observational Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Kuei-Lin Yeh, Sheng-Mou Hou, Shing-Sheng Wu, Department of Orthopedics, Shin Kong Wu Ho-Su Memorial Hospital, Taipei 11101, Taiwan
Szu-Hsien Wu, Department of Physical Medicine and Rehabilitation, Taipei Veterans General Hospital, Taipei 11217, Taiwan
Chen-Kun Liaw, Department of Orthopedics, School of Medicine, College of Medicine, Taipei Medical University, Taipei 11031, Taiwan
Chen-Kun Liaw, Department of Orthopedics, Shuang Ho Hospital, Taipei Medical University, New Taipei 23561, Taiwan
Chen-Kun Liaw, Graduate Institute of Biomedical Optomechatronics, College of Biomedical Engineering, Research Center of Biomedical Device, Taipei Medical University, Taipei 11301, Taiwan
Author contributions: Yeh KL contributed to the study design and interpretation of the data; Wu SH and Liaw CK contributed to the acquisition and analysis of the data, and the creation of new software used in the work; Wu SS assisted in the interpretation of data and drafted the work; Hou SM contributed to the acquisition and analysis of the data and drafted the work.
Institutional review board statement: The study was approved by the institutional review board of Shin-Kong Wu Ho-Su Memorial Hospital, Taiwan (Approval No. 20200608R).
Informed consent statement: The requirement for written consent was waived owing to the retrospective study design.
Conflict-of-interest statement: There are no conflicts of interest to report.
Data sharing statement: The data supporting the findings of this study are available within the article.
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Shing-Sheng Wu, MSc, Professor, Department of Orthopedics, Shin Kong Wu Ho-Su Memorial Hospital, No. 95 Wenchang Road, Shilin District, Taipei 11101, Taiwan. raysswu@gmail.com
Received: July 12, 2021 Peer-review started: July 12, 2021 First decision: August 18, 2021 Revised: August 31, 2021 Accepted: September 8, 2021 Article in press: September 8, 2021 Published online: November 6, 2021
ARTICLE HIGHLIGHTS
Research background
Cement augmentation is an effective surgical treatment for osteoporotic compression fractures. There are several cement augmentation types. However, no studies have compared the safety and efficacy of different cement augmentation types for the treatment of compression fractures.
Research motivation
We performed this study to understand the efficacy of different cement augmentation methods on osteoporotic compression fractures.
Research objectives
The purpose of this study was to investigate the visual analog scale scores for pain, kyphotic angle, average body height, rate of cement leakage, and occurrence of adjacent vertebral compression fractures for each different cement augmentation type.
Research methods
We retrospectively analyzed 354 patients with acute vertebral compression fractures. Visual analog scale scores for pain, kyphotic angle, average body height, rate of cement leakage, and occurrence of adjacent vertebral compression fractures were followed for 1 year and compared among different cement augmentation types.
Research results
In these 354 patients, all cement augmentation types showed significant improvement on pain scores, and no significant difference was noted between the groups (P = 0.325). Kyphoplasty with SpineJack performed best with regard to kyphotic angle reduction (P = 0.028) and vertebral body height restoration (P = 0.02). The rate of adjacent compression fractures was highest in the vertebroplasty group, with a statistically significant difference according to the Fisher’s exact probability test (P = 0.02). Although kyphoplasty with SpineJack, kyphoplasty with an intravertebral expandable pillar (IVEP), and vesselplasty resulted in lower rates of cement leakage than balloon kyphoplasty and vertebroplasty, the results might not be conclusive due to the small sample size.
Research conclusions
Kyphoplasty with SpineJack has good outcomes in sagittal alignment correction. Vertebroplasty has the highest cement leakage rate and adjacent compression fracture occurrence.
Research perspectives
In follow-up studies, more patients will be enrolled to validate and evaluate cement leakage rates in balloon kyphoplasty more accurately with SpineJack, vesselplasty, and an IVEP, and discuss more factors and postoperative outcomes.
