Liu S, Tang MM, Du J, Gong ZC, Sun SS. COVID-19 in gastroenterology and hepatology: Lessons learned and questions to be answered. World J Clin Cases 2021; 9(17): 4199-4209 [PMID: 34141782 DOI: 10.12998/wjcc.v9.i17.4199]
Corresponding Author of This Article
Shu-Sen Sun, PharmD, PhD, Chief Pharmacist, Department of Pharmacy Practice, College of Pharmacy and Health Sciences, Western New England University, 1215 Wilbraham Road, Springfield, MA 01119, United States. shusen.sun@wne.edu
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Systematic Reviews
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Jun 16, 2021; 9(17): 4199-4209 Published online Jun 16, 2021. doi: 10.12998/wjcc.v9.i17.4199
COVID-19 in gastroenterology and hepatology: Lessons learned and questions to be answered
Shao Liu, Mi-Mi Tang, Jie Du, Zhi-Cheng Gong, Shu-Sen Sun
Shao Liu, Mi-Mi Tang, Jie Du, Zhi-Cheng Gong, Department of Pharmacy, Xiangya Hospital, Central South University, Changsha 410008, Hunan Province, China
Shao Liu, Mi-Mi Tang, Jie Du, Zhi-Cheng Gong, Department of Pharmacy, The Hunan Institute of Pharmacy Practice and Clinical Research, Changsha 410008, Hunan Province, China
Shao Liu, Mi-Mi Tang, Jie Du, Zhi-Cheng Gong, Institute of Hospital Pharmacy, Central South University, Changsha 410008, Hunan Province, China
Shu-Sen Sun, Department of Pharmacy Practice, College of Pharmacy and Health Sciences, Western New England University, Springfield, MA 01119, United States
Author contributions: Liu S and Tang MM wrote the manuscript; Du J searched the related literature; Gong ZC and Sun SS revised the manuscript.
Supported bythe Key Research and Development Program of Hunan Province, No. 2020SK3022.
Conflict-of-interest statement: The authors declare no conflict of interests for this article.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Shu-Sen Sun, PharmD, PhD, Chief Pharmacist, Department of Pharmacy Practice, College of Pharmacy and Health Sciences, Western New England University, 1215 Wilbraham Road, Springfield, MA 01119, United States. shusen.sun@wne.edu
Received: January 20, 2021 Peer-review started: January 20, 2021 First decision: February 9, 2021 Revised: February 26, 2021 Accepted: April 23, 2021 Article in press: April 23, 2021 Published online: June 16, 2021
ARTICLE HIGHLIGHTS
Research background
Recent studies suggest multiorgan, including in the gastrointestinal tract and liver, involvement in patients infected by coronavirus disease-2019 (COVID-19).
Research motivation
We hope to raise the unsolved problems of COVID-19 in the field of gastroenterology and hepatology and point out the directions for future research.
Research objectives
The purpose of this paper is to analyze and summarize the critical issues of COVID-19 in the field of gastroenterology and hepatology.
Research methods
We completed this paper by searching many relevant studies and then sorting and analyzing the data.
Research results
Gastrointestinal symptoms and liver damage due to COVID-19 infection can vary depending on the patient.
Research conclusions
Digestive symptoms and liver damage are not uncommon in COVID-19 patients and vary from person to person. But with the development of the disease, further research and exploration are still needed.
Research perspectives
Based on the monitoring of patients infected with COVID-19, gastrointestinal symptoms and liver injury characteristics were summarized.
