Published online Mar 16, 2018. doi: 10.12998/wjcc.v6.i3.20
Peer-review started: November 1, 2017
First decision: November 20, 2017
Revised: December 31, 2017
Accepted: February 28, 2018
Article in press: February 28, 2018
Published online: March 16, 2018
The main objectives of this retrospective trial study were to evaluate whether there was any correlation between the clinical parameters and final pathological results among patients who underwent thyroid surgery.
We retrospectively analyzed the demographic, clinical and histopathological parameters of 505 patients who underwent thyroid surgery. The patients were divided into malignant (n = 92) and benign (n = 413) groups depending on the final pathological results. We analyzed whether there was any difference between the groups in terms of demographic and clinical parameters.
No significant differences were found between the groups with respect to age, sex, WBC count, neutrophil count, lymphocyte count, thrombocyte count, RDW, PDW, MPV, PCT, nodule localization, and thyroid function testing. On the other hand, there were significant differences between the groups with respect to nodule size, cervical lymphadenopathy and nodular calcification. The correlation between FNAB and final pathological results was assessed using the cross-table method, and the sensitivity and specificity for FNAB were 60% and 98%, respectively.
This study showed that significant differences existed between the malignant and benign groups with regard to nodule size, cervical lymphadenopathy, and nodular calcification.