Published online Nov 6, 2018. doi: 10.12998/wjcc.v6.i13.694
Peer-review started: July 31, 2018
First decision: August 31, 2018
Revised: October 3, 2018
Accepted: October 11, 2018
Article in press: October 11, 2018
Published online: November 6, 2018
Processing time: 98 Days and 5.5 Hours
A 64-year-old woman was admitted with intermittent fever for 2 mo.
Stage 4B natural killer (NK)/T-cell lymphoma with concomitant syndrome of inappropriate antidiuretic hormone secretion (SIADH).
Infection, typhia, brucellosis, etc.
As determined by blood and urine sampling examination, serum Na+ was 109.3 mmol/L, urea was 2.99 mmol/L, serum creatinine was 47.8 μmol/L, plasma osmolality was 235.39 mOsm/kg, and urine osmolality was 494 mOsm/kg.
Positron emission tomography-computed tomography indicated multiple swollen lymph nodes throughout the body accompanied by increased fluorodeoxyglucose metabolism, consistent with lymphoma.
Biopsy of the left submandibular lymph nodes confirmed NK/T-cell lymphoma.
Chemotherapy, fluid restriction, and administration of sodium chloride.
This is the first known report of NK/T-cell lymphoma with concomitant SIADH in PubMed.
Lymphoma is one of the causes of SIADH; however, NK/T-cell lymphoma with concomitant SIADH has not been reported.
This case report emphasizes the importance of monitoring serum ions and etiological treatment in patients with NK/T-cell lymphoma.