Retrospective Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Mar 26, 2024; 12(9): 1578-1584
Published online Mar 26, 2024. doi: 10.12998/wjcc.v12.i9.1578
Factors influencing Frey syndrome after parotidectomy with acellular dermal matrix
Xian-Da Chai, Huan Jiang, Ling-Ling Tang, Jing Zhang, Long-Fei Yue
Xian-Da Chai, Huan Jiang, Ling-Ling Tang, Jing Zhang, Department of Oral and Maxillofacial Surgery, People’s Hospital of Anshun, Anshun 561000, Guizhou Province, China
Long-Fei Yue, Department of General Practice, People’s Hospital of Anshun, Anshun 561000, Guizhou Province, China
Author contributions: Chai XD and Yue LF designed the study, analyzed the data and prepared the manuscript; Jiang H, Tang LL and Zhang J collected the data; Chai XD interpreted the data; All authors have read and approved the manuscript.
Institutional review board statement: The study was reviewed and approved by the Anshun People's Hospital Ethics Committee (Approval No. 3).
Informed consent statement: The patient provided informed written consent prior to study enrollment.
Conflict-of-interest statement: The authors declare no conflict-of-interest.
Data sharing statement: Technical appendix, statistical code, and dataset available from the corresponding author at email lonhfei_yue@163.com. Participants gave informed consent for data.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Long-Fei Yue, MD, Chief Doctor, Department of General Practice, People’s Hospital of Anshun, No. 140 Huangguoshu Street, Anshun 561000, Guizhou Province, China. longfei_yue@163.com
Received: November 2, 2023
Peer-review started: November 2, 2023
First decision: January 9, 2024
Revised: January 22, 2024
Accepted: February 25, 2024
Article in press: February 25, 2024
Published online: March 26, 2024
Processing time: 144 Days and 0.3 Hours
ARTICLE HIGHLIGHTS
Research background

Frey syndrome, also known as ototemporal nerve syndrome or guest-sweating syndrome, is one of the most common complications of parotid gland surgery. It is characterized by abnormal facial skin sensations, flushing, or sweating when the patient thinks, sees, or eats.

Research motivation

This inclusion has inadvertently increased the recorded incidence of Frey syndrome. This retrospective study investigated the factors influencing the acellular dermal matrix (ADM) in the prevention of Frey syndrome in patients who have undergone parotid surgery.

Research objectives

Because of the effects of frey syndrome, there was a need to find a way to reduce its incidence

Research methods

The data of 82 patients were retrospectively analyzed using SPSS 25.0, and the correlations between sex, age, resection sample size, operation time, operation mode, ADM use, and postoperative Frey syndrome were analyzed.

Research results

The incidence of Frey syndrome was 56.1% among the 82 patients. There were no significant differences in sex, age, or operation time between the two groups (P > 0.05). There was a significant difference between ADM implantation and the onset of symptoms of Frey syndrome (P < 0.05). ADM can reduce the variation in Frey syndrome onset. ADM can delay the onset of Frey signs.

Research conclusions

the application of ADM affects Frey syndrome prevention. However, it is important to note that ADM degrades within approximately six months, and Frey syndrome may still occur after this degradation. Additionally, controlling the diameter of the excised samples can help prevent the occurrence of Frey syndrome.

Research perspectives

The incidence of Frey syndrome was reduced by surgery and the implantation of ADM.