Retrospective Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Mar 6, 2024; 12(7): 1251-1259
Published online Mar 6, 2024. doi: 10.12998/wjcc.v12.i7.1251
Clinical characteristics of testicular torsion and factors influencing testicular salvage in children: A 12-year study in tertiary center
Xiang-Hui Gang, Yuan-Yuan Duan, Bin Zhang, Zheng-Gan Jiang, Rong Zhang, Jun Chen, Xiang-Yu Teng, Duo-Bing Zhang
Xiang-Hui Gang, Bin Zhang, Zheng-Gan Jiang, Rong Zhang, Jun Chen, Duo-Bing Zhang, Department of Urology, Suzhou Hospital Affiliated to Anhui Medical University, Suzhou 234000, Anhui Province, China
Yuan-Yuan Duan, Department of Ultrasound Diagnosis, Suzhou Hospital Affiliated to Anhui Medical University, Suzhou 234000, Anhui Province, China
Xiang-Yu Teng, Department of Urology, The Second Affiliated Hospital of Anhui Medical University, Hefei 230000, Anhui Province, China
Co-first authors: Xiang-Hui Gang and Yuan-Yuan Duan.
Author contributions: Gang XH study conception and design, analysis and data interpretation, drafting of the manuscript, and critical revision; Duan YY, Jiang ZG and Teng XY study conception and design, data acquisition, and critical revision; Zhang B, Zhang R, and Chen J data acquisition, analysis, interpretation, and critical revision; Zhang DB study conception and design, analysis and data interpretation, drafting of the manuscript, and critical revision.
Supported by Anhui Province Translational Medicine Research Fund Project, No. 2021zhyx-C59 and No. 2021zhyx-C75.
Institutional review board statement: The study was reviewed and approved by the Ethics Committee of Anhui Medical University Suzhou Hospital Institutional Review Board, Approval No. A2023006.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Duo-Bing Zhang, MD, Academic Research, Surgeon, Department of Urology, Suzhou Hospital Affiliated to Anhui Medical University, No. 299 Bianhe Middle Road, Suzhou 234000, Anhui Province, China. zhangduobingsz@126.com
Received: November 26, 2023
Peer-review started: November 26, 2023
First decision: December 29, 2023
Revised: January 9, 2024
Accepted: February 4, 2024
Article in press: February 4, 2024
Published online: March 6, 2024
Processing time: 95 Days and 18.7 Hours
ARTICLE HIGHLIGHTS
Research background

Testicular torsion (TT) is currently the leading cause of testicular removal in adolescents, with an incidence rate of 1 in 4000 among males under the age of 25. Delayed medical consultation for TT and misdiagnosis could lead to orchiectomy. Therefore, we aim to analyze the factors influencing orchiectomy or testicular salvage by reviewing the data of patients who presented at our center.

Research motivation

Various factors, such as delayed presentation to the healthcare facility and excessive degree of torsion, can lead to orchiectomy in adolescents with TT. Hence, we conducted a retrospective analysis of data from our center to identify the factors affecting the prognosis of TT.

Research objectives

Factors to predict the possibility of testicular salvage (TS) in patients with TT in our tertiary center.

Research methods

By collecting clinical data from patients with TT treated at our center, we performed univariate and multivariate regression analyses to compare between the TS and the orchiectomy group.

Research results

Our study has identified that younger age, body mass index, torsion angle, red blood cell count and neutrophil-to-lymphocyte ratio have predictive value for TS. And we found a new factor that the type of institution where patients first presented as a predictive factor for the outcome of TT; patients who initially presented to a tertiary-care hospital were more likely to have testicular preservation.

Research conclusions

The initial presenting institution is a new predictive factor for outcome of TT. Patients with scrotal pain should be presented to a tertiary hospital as soon as possible.

Research perspectives

Future research will focus on enhancing public health education regarding scrotal emergencies to prevent delays in the presentation of patients with conditions such as TT.