Retrospective Study
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jan 26, 2023; 11(3): 556-565
Published online Jan 26, 2023. doi: 10.12998/wjcc.v11.i3.556
Qixue Shuangbu decoction and acupuncture combined with Western medicine in acute severe stroke patients
Li-Kun Gou, Chun Li
Li-Kun Gou, Chun Li, Department of Critical Care Medicine, Lanzhou Second People’s Hospital, Lanzhou 730046, Gansu Province, China
Author contributions: Gou LK and Li C design the study; Gou LK drafted the manuscript; Gou LK and Li C collected the data; Li C analyzed and interpreted data, Gou LK and Li C wrote and revised the manuscript.
Supported by Lanzhou Science and Technology Development Plan Project, No. 2020-ZD-126.
Institutional review board statement: The study was reviewed and approved by the Lanzhou Second People’s Hospital Institutional Review Board.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: The authors declare no conflict of interest.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Chun Li, MD, Chief Doctor, Department of Critical Care Medicine, Lanzhou Second People’s Hospital, No. 388 Jingyuan Road, Lanzhou 730046, Gansu Province, China. lanzhoulichun@126.com
Received: May 6, 2022
Peer-review started: May 6, 2022
First decision: May 30, 2022
Revised: June 18, 2022
Accepted: December 21, 2022
Article in press: December 21, 2022
Published online: January 26, 2023
Processing time: 265 Days and 7 Hours
ARTICLE HIGHLIGHTS
Research background

Stroke is a common and frequently occurring disease of the nervous system and one of the three major diseases leading to human death.

Research motivation

The effects of Qixue Shuangbu decoction and acupuncture combined with Western medicine on immune indexes and digestive tract function in patients with acute severe stroke were analyze.

Research objectives

This study aimed to observe the curative effect of Qixue Shuangbu Decoction and acupuncture combined with Western medicine on acute severe stroke, with the purpose of improving the clinical therapeutic effect.

Research methods

The observation group was administered Qixue Shuangbu decoction via nasal feeding tube on the basis of the routine Western medicine treatment with simultaneous acupuncture. The two groups were compared.

Research results

After treatment, the scores of the observation group were lower than those of the control group, and the complement and Ig levels were higher than those of the control group. The levels of diamine oxidase, D-lactic acid, and calcitonin gene-related peptide in the two groups were significantly higher than those before treatment, while the levels of lipopolysaccharide, ubiquitin carboxyl-terminal hydrolase 1, tumor necrosis factor-α, interleukin (IL) -2, and IL-8 were significantly lower than those before treatment.

Research conclusions

Qixue Shuangbu decoction and acupuncture combined with Western medicine for the treatment of acute severe stroke can regulate intestinal flora.

Research perspectives

The immune function and digestive tract function indexes were selected as the observation objects to analyze the therapeutic effect of integrated traditional Chinese and Western medicine to provide the corresponding basis for clinical practice.