Wang J, Yao QY, Zhu HY. Efficacy of bone grafts in jaw cystic lesions: A systematic review. World J Clin Cases 2022; 10(9): 2801-2810 [PMID: 35434117 DOI: 10.12998/wjcc.v10.i9.2801]
Corresponding Author of This Article
Hui-Yong Zhu, MD, PhD, Professor, Department of Oral and Maxillofacial Surgery, First Affiliated Hospital, College of Medicine, Zhejiang University, No. 79 Qingchun Road, Hangzhou 310003, Zhejiang Province, China. zhuhuiyong@zju.edu.cn
Research Domain of This Article
Dentistry, Oral Surgery & Medicine
Article-Type of This Article
Systematic Reviews
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Mar 26, 2022; 10(9): 2801-2810 Published online Mar 26, 2022. doi: 10.12998/wjcc.v10.i9.2801
Efficacy of bone grafts in jaw cystic lesions: A systematic review
Jin Wang, Qiu-Yun Yao, Hui-Yong Zhu
Jin Wang, Qiu-Yun Yao, Hui-Yong Zhu, Department of Oral and Maxillofacial Surgery, First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, Zhejiang Province, China
Author contributions: Wang J and Zhu HY designed the research; Wang J and Yao QY performed the literature research and data analysis; Wang J performed the drafting of paper; Zhu HY made the final approval; all authors have read and approved the final manuscript.
Conflict-of-interest statement: All the authors declare that they have no competing interests.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hui-Yong Zhu, MD, PhD, Professor, Department of Oral and Maxillofacial Surgery, First Affiliated Hospital, College of Medicine, Zhejiang University, No. 79 Qingchun Road, Hangzhou 310003, Zhejiang Province, China. zhuhuiyong@zju.edu.cn
Received: September 22, 2021 Peer-review started: September 22, 2021 First decision: December 10, 2021 Revised: December 23, 2021 Accepted: February 15, 2022 Article in press: February 15, 2022 Published online: March 26, 2022 Processing time: 180 Days and 23.8 Hours
ARTICLE HIGHLIGHTS
Research background
Bone grafts have been widely applied in orthopedic surgery, but their efficacy in relation to bone regeneration in jaw cystic lesions remains unclear.
Research motivation
To identify whether bone grafts are beneficial for bone regeneration in jaw cystic lesions and when bone grafts should be used.
Research objectives
To study the level of bone regeneration after bone grafting compared to spontaneous healing in the treatment of jaw cystic lesions.
Research methods
A literature search was performed in Medline, Cochrane Library and Embase to identify related articles published in English in the last ten years. Articles without assessment of bone regeneration or uniform follow-up time were excluded. Case reports, clinical trials, clinical studies, observational studies and randomized controlled trials were included.
Research results
Ten studies were included. Over 90% of bone regeneration occurred within 6 mo after bone grafting. The bone regeneration rate after cystectomy ranged from 50% to 100% after 6 mo, but reached over 90% after 12 mo.
Research conclusions
Bone grafts accelerate the process of healing and significantly increase bone quality, but the long-term superiority of bone grafting compared with spontaneous healing after cystectomy is unclear.
Research perspectives
There is a need for future studies with better assessment methods, variable control and strict randomized design, as well as longer follow-up time.
