Zhuo MF, Zhang KL, Shen XB, Lin WC, Hu B, Cai HP, Huang G. Postoperative adverse cardiac events in acute myocardial infarction with high thrombus load and best time for stent implantation. World J Clin Cases 2022; 10(7): 2106-2114 [PMID: 35321185 DOI: 10.12998/wjcc.v10.i7.2106]
Corresponding Author of This Article
Gang Huang, BM BCh, Chief Doctor, Department of Emergency, Shishi General Hospital, Shishi 362700, No. 2156 Shijin Road, Fujian Province, China. huanggangdoctor@163.com
Research Domain of This Article
Emergency Medicine
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Mar 6, 2022; 10(7): 2106-2114 Published online Mar 6, 2022. doi: 10.12998/wjcc.v10.i7.2106
Postoperative adverse cardiac events in acute myocardial infarction with high thrombus load and best time for stent implantation
Ming-Feng Zhuo, Ke-Lian Zhang, Xue-Bin Shen, Wen-Can Lin, Bin Hu, Hua-Peng Cai, Gang Huang
Ming-Feng Zhuo, Wen-Can Lin, Bin Hu, Hua-Peng Cai, Gang Huang, Department of Emergency, Shishi General Hospital, Shishi 362700, Fujian Province, China
Ke-Lian Zhang, Department of Cardiovascular, Quanzhou First Hospital, Quanzhou 362000, Fujian Province, China
Xue-Bin Shen, Department of Cardiology, Affiliated Nanping First Hospital, Fujian Medical University, Nanping 353000, Fujian Province, China
Author contributions: Zhuo MF and Zhang KL contributed equally to this article and should be regarded as co-first authors; Zhuo MF and Zhang KL designed the experiment; Shen XB drafted the work; Lin WC, Hu B, and Cai HP collected the data; Huang G and Zhuo MF analyzed and interpreted data; Zhang KL, Shen XB, and Lin WC wrote the manuscript.
Supported byQuanzhou Science and Technology Bureau Approved the Project, Quanzhou Science and Technology Plan Project, No. 2019N008S.
Institutional review board statement: This study was approved by Medical Ethics Committee of Shishi General Hospital.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: No conflict of interest.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Gang Huang, BM BCh, Chief Doctor, Department of Emergency, Shishi General Hospital, Shishi 362700, No. 2156 Shijin Road, Fujian Province, China. huanggangdoctor@163.com
Received: November 24, 2021 Peer-review started: November 24, 2021 First decision: December 9, 2021 Revised: December 17, 2021 Accepted: January 22, 2022 Article in press: January 22, 2022 Published online: March 6, 2022 Processing time: 97 Days and 18.6 Hours
ARTICLE HIGHLIGHTS
Research background
Myocardial infarction is one of the most common types of coronary heart disease. The occlusion of coronary arteries and blood vessels leads to insufficient blood supply to the myocardium, which in turn leads to cardiac interstitial fibrosis, gradual expansion of the ventricles, and heart failure, which affect the quality of life and safety of patients.
Research motivation
This study explored the treatment of myocardial infarction.
Research objectives
This study aimed to investigate the effects of emergency percutaneous interventional therapy (PCI) and delayed stenting in acute myocardial infarction with high thrombotic load and identify factors related to major adverse cardiovascular events (MACE).
Research methods
A total of 164 patients with acute myocardial infarction and high thrombotic load who received PCI were included.
Research results
After stent placement, 66 patients in the delayed group and 40patients in the immediate group were classified as thrombolysis in myocardial infarction (TIMI) blood flow grade 3, 61 patients and 39 patients in the delayed group. MACE occurred in 29 patients. The MACE group and the non-MACE group had statistically significant differences in the incidence of diabetes, TIMI classification, timing of stent placement, etc.
Research conclusions
Delayed stent implantation outweighs emergency PCI in improving postoperative myocardial perfusion in acute myocardial infarction with high thrombotic load, and effectively reduces MACE in these patients.
Research perspectives
It has certain reference significance for the treatment of acute myocardial infarction.
