Feng XD, Xie X, He R, Li F, Tang GZ. Doctor-led intensive diet education on health-related quality of life in patients with chronic renal failure and hyperphosphatemia. World J Clin Cases 2022; 10(4): 1217-1225 [PMID: 35211555 DOI: 10.12998/wjcc.v10.i4.1217]
Corresponding Author of This Article
Gui-Zhong Tang, MD, Assistant Technician, Chongqing Medical University School of Public Health and Management, Medical and Social Development Research Center, and Collaborative Innovation Center for Social Risk Prediction and Governance in the Health Field, No. 1 Yixueyuan Road, Yuzhong District, Chongqing 400016, China. tangguizhong968@163.com
Research Domain of This Article
Urology & Nephrology
Article-Type of This Article
Observational Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Xian-Dong Feng, Xue Xie, Rui He, Fang Li, Medical Department, Chengdu Second People’s Hospital, Chengdu 610021, Sichuan Province, China
Gui-Zhong Tang, Chongqing Medical University School of Public Health and Management, Medical and Social Development Research Center, and Collaborative Innovation Center for Social Risk Prediction and Governance in the Health Field, Chongqing 400016, China
Author contributions: Feng XD and Tang GZ design the experiment; Xie X drafted the work, Li F and He R collected the data; Feng XD, Li F and He R analysed and interpreted data, Feng XD and Tang GZ wrote the article.
Institutional review board statement: This study was approved by the Chengdu Second People’s Hospital Ethics Committee.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: The authors declared that there is no conflict of interest between them.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Gui-Zhong Tang, MD, Assistant Technician, Chongqing Medical University School of Public Health and Management, Medical and Social Development Research Center, and Collaborative Innovation Center for Social Risk Prediction and Governance in the Health Field, No. 1 Yixueyuan Road, Yuzhong District, Chongqing 400016, China. tangguizhong968@163.com
Received: October 15, 2021 Peer-review started: October 15, 2021 First decision: December 1, 2021 Revised: December 12, 2021 Accepted: December 23, 2021 Article in press: December 23, 2021 Published online: February 6, 2022
ARTICLE HIGHLIGHTS
Research background
Secondary hyperparathyroidism, renal osteodystrophy, and cardiovascular adverse events can occur if long-term hyperphosphatemia is not corrected, leading to the adverse prognosis of patients with chronic renal failure. The clinical control measures for hyperphosphatemia in these patients include diet control.
Research motivation
Provide reference for the treatment of patients with chronic renal failure and hyperphosphatemia.
Research objectives
This study aimed to observe doctor-led intensive diet education effects on health-related quality of life, in patients with chronic renal failure and hyperphosphatemia.
Research methods
We assessed 120 patients with chronic renal failure hemodialysis and hyperphosphatemia admitted to our hospital (July 2018–March 2020). The levels of serum parathyroid hormone (iPTH), calcium (Ca), phosphorus (P), calcium-phosphorus product (Ca × P), serum creatinine (Scr), and blood urea nitrogen (BUN) before intervention and 3 and 6 mo after intervention in the groups were assessed.
Research results
After 3 mo and 6 mo of intervention, the blood iPTH, Ca, P and Ca × P in the two groups decreased gradually, but there was no significant difference in Scr and BUN. The blood iPTH, Ca, P and Ca × P in the observation group were lower than those in the control group. The overall EQ-5D-3L score of the observation group was better than that of the control group. The scores of disease-related knowledge and compliance were higher in the observation group than in the control group.
Research conclusions
Doctor-led intensive diet education can improve the quality of life of patients with chronic renal failure and hyperphosphatemia, promote low-phosphorus diet behavior, and improve patient satisfaction.
Research perspectives
Exploring treatment approaches for patients with chronic renal failure and hyperphosphatemia can provide references for clinical work in the future.
