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©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Dec 26, 2022; 10(36): 13313-13320
Published online Dec 26, 2022. doi: 10.12998/wjcc.v10.i36.13313
Published online Dec 26, 2022. doi: 10.12998/wjcc.v10.i36.13313
Thoracic para-aortic lymph node recurrence in patients with esophageal squamous cell carcinoma: A propensity score-matching analysis
Xu-Yuan Li, Shu-Han Yu, Department of Medical Oncology, Shantou Central Hospital, Shantou 515041, Guangdong Province, China
Li-Sheng Huang, Department of Radiation Oncology, Cancer Hospital of Shantou University Medical College, Shantou 515041, Guangdong Province, China
Dan Xie, Department of Radiology, Shantou Central Hospital, Shantou 515041, Guangdong Province, China
Author contributions: Li XY and Huang LS contributed equally to this work; Li XY designed the research study; Xie D and Yu SH performed the research; Li XY, Huang LS, Xie D and Yu SH analyzed the data and wrote the manuscript; and all authors have read and approve the final manuscript.
Institutional review board statement: Approval for the use of medical records was obtained from the Ethics Committees of Shantou Central Hospital, China, prior to the study. All study protocols were approved by this committee.
Informed consent statement: Informed consent was waived by the IRB of the Shantou Central Hospital.
Conflict-of-interest statement: All the authors report having no relevant conflicts of interest for this article.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xu-Yuan Li, MM, Doctor, Department of Medical Oncology, Shantou Central Hospital, No. 114 Waima Road, Shantou 515041, Guangdong Province, China. lxuyuan@qq.com
Received: October 7, 2022
Peer-review started: October 7, 2022
First decision: November 11, 2022
Revised: November 13, 2022
Accepted: December 5, 2022
Article in press: December 5, 2022
Published online: December 26, 2022
Processing time: 80 Days and 4.6 Hours
Peer-review started: October 7, 2022
First decision: November 11, 2022
Revised: November 13, 2022
Accepted: December 5, 2022
Article in press: December 5, 2022
Published online: December 26, 2022
Processing time: 80 Days and 4.6 Hours
ARTICLE HIGHLIGHTS
Research background
Thoracic para-aortic lymph nodes (TPLNs) recurrence in esophageal squamous cell carcinoma (ESCC) is rare but with poor survival outcomes in clinical observation.
Research motivation
TPLNs recurrence had negative impact on survival outcomes in patients with ESCC.
Research objectives
TPLN (+) was associated with worse recurrence-free and overall survival (OS) in patients with ESCC.
Research methods
The propensity score-matching and survival estimation were applied, and factors predictive of OS were explored using a Cox proportional hazards model.
Research results
To study survival in patients with ESCC who developed TPLNs recurrence.
Research conclusions
To determine TPLNs recurrence rate and its impact on survival.
Research perspectives
TPLNs recurrence in ESCC is rare but with poor survival outcomes in clinical observation.