Published online Dec 6, 2022. doi: 10.12998/wjcc.v10.i34.12543
Peer-review started: June 19, 2022
First decision: July 29, 2022
Revised: October 16, 2022
Accepted: November 17, 2022
Article in press: November 17, 2022
Published online: December 6, 2022
It is estimated that approximately 75000 new cases of cervical cancer occur every year in China. In 2008, 33000 people died of cervical cancer in China. It is proven that most women are at risk of cervical cancer.
The progression from human papillomavirus (HPV) infection to cervical cancer can be several years or decades, which offers a unique opportunity to prevent cancer.
To observe the changes in ThinPrep cytology tests (TCT) and HPV infection in patients who were positive via TCT screening of cervical cancer and to further explore the biopsy results.
This paper performed a follow-up study on 206 cervical cancer screening-positive patients of 12231 total cases from our previous research. We conducted an observational study on the TCT results based on the interpretation of The Bethesda System.
The follow-up study of 5-9 years revealed a tendency to improve from squamous epithelial lesions to glandular epithelial lesions (which had not been reported previously).
Early intervention of cervical cancer screening is necessary. Low re-examination compliance, patient education, and preventive measures should be enhanced.
Women should have regular gynecological physical examinations to check for HPV infection. Early detection, accurate typing, and virus quantification of HPV infection are of great significance for the prevention and treatment of cervical cancer.