Retrospective Study
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jul 26, 2022; 10(21): 7324-7332
Published online Jul 26, 2022. doi: 10.12998/wjcc.v10.i21.7324
Effects of alendronate sodium combined with InterTan on osteoporotic femoral intertrochanteric fractures and fracture recurrence
Ke-Meng Wang, Shi-Ping Wei, Xiao-Yan Yin, Qing-Ju Meng, Yu-Ming Kong
Ke-Meng Wang, Qing-Ju Meng, Department of Orthopedics, First Affiliated Hospital of Xingtai Medical College, Xingtai 054001, Hebei Province, China
Shi-Ping Wei, Xiao-Yan Yin, Department of Basic Medicine, Xingtai Medical College, Xingtai 054001, Hebei Province, China
Yu-Ming Kong, Department of Orthopedics, The First Hospital of Xingtai, Xingtai 054001, Hebei Province, China
Author contributions: Wang KM designed this study; Wang KM and Wei SP wrote the manuscript; Wang KM, Wei SP, Yin XY, Meng QJ, and Kong YM were responsible for sorting the data; and all authors have read and approve the final manuscript.
Supported by Special Projects for Social Development Areas.
Institutional review board statement: The study was reviewed and approved by The First Hospital of Xingtai Institutional Review Board.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: All authors declare no conflict of interest.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ke-Meng Wang, MD, Associate Chief Physician, Department of Orthopedics, First Affiliated Hospital of Xingtai Medical College, No. 376 Shunde Road, Xiangdu District, Xingtai 054001, Hebei Province, China. wangkemeng1979@163.com
Received: March 15, 2022
Peer-review started: March 15, 2022
First decision: April 19, 2022
Revised: April 27, 2022
Accepted: June 27, 2022
Article in press: June 21, 2022
Published online: July 26, 2022
Processing time: 117 Days and 23 Hours
ARTICLE HIGHLIGHTS
Research background

It is estimated that 1.6 million patients develop wrist fractures worldwide due to osteoporosis.

Research motivation

The osteoporotic intertrochanteric fracture is one of the most common complications of osteoporosis and requires surgical internal fixation.

Research objectives

This study aimed to examine the effect of alendronate sodium combined with InterTan for osteoporotic femoral intertrochanteric fractures on bone and fracture recurrence

Research methods

The control group was treated with InterTan fixation combined with placebo, and the observation group with alendronate sodium based on InterTan fixation.

Research results

The fracture healing time was significantly shorter in the observation group than in the control group.

Research conclusions

Alendronate sodium combined with InterTan in the treatment of osteoporotic intertrochanteric fractures can reduce fracture recurrence.

Research perspectives

Osteoporosis is a significant public health concern in aging societies and can cause pain and fractures