Retrospective Study
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jul 26, 2022; 10(21): 7302-7313
Published online Jul 26, 2022. doi: 10.12998/wjcc.v10.i21.7302
Risk factors for delayed intracranial hemorrhage secondary to ventriculoperitoneal shunt: A retrospective study
Jun-Chen Chen, Shou-Xing Duan, Ze-Bin Xue, Sen-Yuan Yang, Yong Li, Run-Long Lai, Dian-Hui Tan
Jun-Chen Chen, Ze-Bin Xue, Sen-Yuan Yang, Yong Li, Run-Long Lai, Dian-Hui Tan, Department of Neurosurgery, First Affiliated Hospital of Shantou University Medical College, Shantou 515041, Guangdong Province, China
Shou-Xing Duan, Department of Pediatric Surgery, First Affiliated Hospital of Shantou University Medical College, Shantou 515041, Guangdong Province, China
Shou-Xing Duan, Department of Pediatric Surgery, Huazhong University of Science and Technology Union Shenzhen Hospital, Shenzhen 518052, Guangdong Province, China
Author contributions: Chen JC was considered as first author; Chen JC, Xue ZB, Yang SY, Li Y, Lai RL and Tan DH participated in the patient treatment; Chen JC, Xue ZB and Yang SY collected the clinical data and performed the literature; Chen JC and Duan SX wrote the manuscript; Tan DH helped to design and revise the paper.
Supported by Shantou Medical Healthcare Science and Technology Program, No. [2019]70; Natural Science Foundation of Guangdong Province of China, No. 2022A1515010407; and Guangdong Provincial Science and Technology Fund ("major special project + Task list") for high-level hospital construction, No. STKJ2021119.
Institutional review board statement: This retrospective study was reviewed and approved by the Ethics Committee of The First Affiliated Hospital of Shantou University Medical College, No. 2019034.
Informed consent statement: All study participants or their legal guardian provided informed written consent about personal and medical data collection prior to study enrolment.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Dian-Hui Tan, MD, Doctor, Department of Neurosurgery, First Affiliated Hospital of Shantou University Medical College, No. 57 Changping Road, Shantou 515041, Guangdong Province, China. tandianhui@163.com
Received: November 13, 2021
Peer-review started: November 13, 2021
First decision: April 7, 2022
Revised: April 17, 2022
Accepted: May 26, 2022
Article in press: May 26, 2022
Published online: July 26, 2022
Processing time: 239 Days and 20.5 Hours
ARTICLE HIGHLIGHTS
Research background

Delayed intracranial hemorrhage (DICH), one of the high mortality complications in ventriculoperitoneal (VP) shunt patients, has not been fully recognized.

Research motivation

To explore the risk factors of delay intracranial hemorrhage and reduce the incidence of this complication in VP shunt patients.

Research objectives

To explore the potential risk factors and mechanisms of delay intracranial hemorrhage in VP shunt patients.

Research methods

We collected the demographic and clinical characteristics data of VP shunt patients between January 2016 and December 2020. DICH group and Non-DICH group were compared in a retrospective study.

Research results

A history of an external ventricular drain and postoperative brain edema around the catheter were related to a high risk for DICH statistically. There was a significant difference in the postoperative modified Rankin Scale scores at the 3-mo follow-up in these two groups.

Research conclusions

A history of an EVD and postoperative brain edema around the catheter were risk factors of DICH VP shunt patients. DICH patients are vulnerable to poor clinical outcomes with a high mRS score.

Research perspectives

More samples from different populations and centers should be included in future studies. The follow-up evaluation needs to be replaced by a more objective method to verify the prognosis.