Retrospective Study
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jan 14, 2022; 10(2): 511-517
Published online Jan 14, 2022. doi: 10.12998/wjcc.v10.i2.511
Effect of Mirena placement on reproductive hormone levels at different time intervals after artificial abortion
Xiao-Xiao Jin, Ling Sun, Xiao-Li Lai, Jie Li, Mei-Li Liang, Xia Ma
Xiao-Xiao Jin, Ling Sun, Xiao-Li Lai, Jie Li, Mei-Li Liang, Xia Ma, Department of Obstetrics and Gynecology, Zhejiang Taizhou Hospital, Taizhou 317000, Zhejiang Province, China
Author contributions: Jin XX and Ma X designed this retrospective study, Jin XX and Sun L wrote this paper; Jin XX, Sun L, Lai XL, Li J, Liang ML and Ma X were responsible for sorting the data.
Institutional review board statement: The study was reviewed and approved by the Zhejiang Taizhou Hospital Institutional Review Board.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: We have no financial relationships to disclose.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xia Ma, MM, PhD, Chief Doctor, Department of Obstetrics and Gynecology, Zhejiang Taizhou Hospital, No. 150 West Gate Street, Taizhou 317000, Zhejiang Province, China. mx20081010@163.com
Received: September 9, 2021
Peer-review started: September 9, 2021
First decision: October 18, 2021
Revised: October 24, 2021
Accepted: December 8, 2021
Article in press: December 8, 2021
Published online: January 14, 2022
Processing time: 124 Days and 18.4 Hours
ARTICLE HIGHLIGHTS
Research background

Placement of an intrauterine device (IUD), such as the Mirena, after an artificial abortion may decrease the likelihood of an endometrial injury caused by recurrent abortions while significantly improving its contraceptive effects.

Research motivation

To discuss the effect of Mirena placement on reproductive hormone levels at different time points after an artificial abortion.

Research objectives

Placement of appropriate IUD after induced abortion can improve the contraceptive effect of patients, reduce adverse reactions caused by contraception, and provide reference for clinical contraceptive treatment.

Research methods

Serum levels of estradiol, follicle-stimulating hormone, luteinizing hormone in patients and the continuation and expulsion rates undergoing different birth control regimens were retrospectively compared.

Research results

The recurrence rates of the two groups were 94.64% and 93.65%, respectively, and there was no significant difference in exclusion rates and adverse reactions. There was no significant difference between the two groups in the proportion of bacterial vaginitis, trichomonas vaginitis, or cervicitis. Six months after Mirena placement, there was no significant difference in hormone levels between the two groups. After the placement of Mirena, there was no significant difference in the proportion of abnormal menstruation, prolonged menstruation and painful intercourse between the study group and the control group. Before and after Mirena placement, there were no significant differences in uterine volume, sexual desire, sexual activity and sexual satisfaction scores between the study group and the control group.

Research conclusions

Placement of a Mirena intrauterine device immediately after an artificial abortion does not increase the risk of adverse reactions and can help prevent endometrial injury caused by recurrent abortions.

Research perspectives

This study took a small number of samples, and the next research direction was to explore the birth control effects of different intrauterine devices.