Retrospective Study
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jul 6, 2022; 10(19): 6446-6455
Published online Jul 6, 2022. doi: 10.12998/wjcc.v10.i19.6446
Effect of cold snare polypectomy for small colorectal polyps
Qing-Qing Meng, Min Rao, Pu-Jun Gao
Qing-Qing Meng, Min Rao, Department of Hepatology and Gastroenterology, The Second Part of First Hospital of Jilin University, Changchun 130021, Jilin Province, China
Pu-Jun Gao, Department of Hepatology, The First Hospital of Jilin University, Changchun 130021, Jilin Province, China
Author contributions: Meng QQ, Rao M and Gao PJ have all participated in the design of this study; Meng QQ and Gao PJ were responsible for analyzing and processing the data; Rao M collected the data in this study; Meng QQ wrote the manuscript, and Gao PJ made the final revision to the manuscript; all the authors have read and approved the final manuscript.
Institutional review board statement: The study was reviewed and approved by the Institutional Review Board of the First Hospital of Jilin University.
Informed consent statement: All study participants, or their legal guardian, had provided verbal consent prior to study enrollment.
Conflict-of-interest statement: Meng QQ, Rao M, Gao PJ are employees of the First Hospital of Jilin University.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Pu-Jun Gao, PhD, Full Professor, Department of Hepatology, The First Hospital of Jilin University, No. 71 Xinmin Street, Changchun 130021, Jilin Province, China. gpj@jlu.edu.cn
Received: January 24, 2022
Peer-review started: January 24, 2022
First decision: April 7, 2022
Revised: April 29, 2022
Accepted: June 15, 2022
Article in press: June 15, 2022
Published online: July 6, 2022
Processing time: 151 Days and 2 Hours
ARTICLE HIGHLIGHTS
Research background

Colorectal cancer remains a considerable challenge in healthcare nowadays and resection of intestinal polyps has been proved to reduce the incidence of colorectal cancer. Cold snare polypectomy (CSP) and hot snare polypectomy (HSP) are the common endoscopic therapy. In this study, we compared the efficacy and safety of CSP and HSP.

Research motivation

HSP is a traditional method that has been used for many years and the incidence of complications is high because of its high frequency electrocoagulation. In recent years, CSP has become the first choice for endoscopists for the advantages of time saving, convenience and less complications. This randomized controlled study was carried out to compare the operating time, incidence of bleeding and perforation, use of titanium clips, and complete resection rate.

Research objectives

To investigate the efficacy and safety of CSP and HSP in the treatment of colorectal polyps with a diameter of 4-9 mm, and to discuss whether it can improve the complete resection rate and resection depth in combination with other endoscopic techniques.

Research methods

From January 2020 to December 2020, a total of 301 patients with colorectal polyps 4-9 mm in size were treated with endoscopic therapy in our hospital, and were divided into the CSP group (n = 154) and HSP group (n = 147). The operation time, incidence of bleeding and perforation, use of titanium clips and complete resection rate of histology were compared between the two groups.

Research results

Two hundred and forty-nine patients (301 polyps) were included in the study. No differences in gender, age, polyp size, location, shape and type were observed between the CSP and HSP groups, and the resection rates in these two groups were 93.4% and 94.5%, respectively, with no significant difference. The use of titanium clips was 15.6% and 95.9%, respectively. The operating time was 3.2 ± 0.5 min and 5.6 ± 0.8 min, the delayed bleeding rate in the two groups was 0% and 2.0%, and delayed perforation was 0% and 0.7%, respectively.

Research conclusions

In the treatment of sessile colorectal polyps < 10 mm, CSP has the same resection rate of impaired tissue integrity as HSP, but the delayed bleeding and perforation rate are lower in CSP group. CSP is a safe and effective method for polypectomy.

Research perspectives

This study retrospectively analyzed patients with colorectal polyps 4-9 mm in size treated by endoscopy in our hospital from January 2020 to December 2020. A comparison of HSP and CSP was carried including surgical outcome and safety.