Randomized Controlled Trial
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jun 26, 2022; 10(18): 6060-6068
Published online Jun 26, 2022. doi: 10.12998/wjcc.v10.i18.6060
Evaluation of the clinical efficacy and safety of TST33 mega hemorrhoidectomy for severe prolapsed hemorrhoids
Liu Tao, Jun Wei, Xu-Feng Ding, Li-Jiang Ji
Liu Tao, Jun Wei, Xu-Feng Ding, Li-Jiang Ji, Department of Anorectal Surgery, Changshu Hospital Affiliated to Nanjing University of Chinese Medicine, Changshu 215500, Jiangsu Province, China
Author contributions: Tao L and Wei J design the study; Ding XF drafted the manuscript, Ji L and Tao L collected the data; Tao L and Ji L analyzed and interpreted data, Tao L and Wei J revised the manuscript.
Supported by Special Project of Diagnosis and Treatment Technology for Key Clinical Diseases in Suzhou, No. LCZX202022; and Changshu Municipal Science and Technology Bureau Supporting Project, No. CS201925.
Institutional review board statement: This study was approved by the Changshu Hospital Affiliated to Nanjing University of Chinese Medicine.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: All authors report no conflict of interest.
Data sharing statement: No additional data are available.
CONSORT 2010 statement: The authors have read the CONSORT 2010 statement, and the manuscript was checked according to the CONSORT 2010 statement.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Li-Jiang Ji, MD, Chief Doctor, Department of Anorectal Surgery, Changshu Hospital Affiliated to Nanjing University of Chinese Medicine, No. 6 Huanghe Road, Changshu 215500, Jiangsu Province, China. ji512@163.com
Received: December 15, 2021
Peer-review started: December 15, 2021
First decision: January 26, 2022
Revised: February 8, 2022
Accepted: April 25, 2022
Article in press: April 25, 2022
Published online: June 26, 2022
Processing time: 183 Days and 16.9 Hours
ARTICLE HIGHLIGHTS
Research background

Although traditional treatment has certain curative effect, it is not ideal. Postoperative symptom relief rate is low. Even if temporarily relieved, hemorrhoids patients are easy to relapse.

Research motivation

In this study, the authors further summarized and analyzed the surgical treatment methods for patients with severe prolapsed hemorrhoids, and compared the effect of TST33 mega staplers to provide a basis for clinical practice.

Research objectives

This study aimed to explore the effect of TST33 mega stapler prolapse and hemorrhoid mucosal resection in the treatment of patients with severe prolapsed hemorrhoids.

Research methods

A total of 204 patients with severe prolapsed hemorrhoids that were admitted to the anorectal department of our hospital from April 2018 to June 2020 were selected and randomly divided into Group A and Group B, with 102 cases in each group, by a single-blind, randomized and controlled clinical research scheme.

Research results

This study found that the operation time, intraoperative blood loss and hospitalization time in Group A were lower than those in Group B, suggesting that the use of TST33 mega stapler hemorrhoid mucosal resection in the treatment of severe prolapsed hemorrhoids has reduced trauma and shorter hospitalization times, which is basically consistent with the conclusions of previous studies, TST33 mega stapler hemorrhoid mucosal resection surgery has a large window vision, and the operation is smoother. This study also showed that the visual analogue scale scores at 12 h and 24 h after the operation in Group A were lower than those in Group B, suggesting that TST33 mega stapler mucosal resection for severe prolapsed hemorrhoids could significantly reduce postoperative pain.

Research conclusions

TST33 mega stapler hemorrhoid mucosal resection in the treatment of severe prolapsed hemorrhoids patients yielded satisfactory results, less postoperative pain, perianal edema recovery block, and fewer complications.

Research perspectives

This study analyzed the advantages of TST33 mega stapler hemorrhoid mucosal resection in the treatment of severe prolapsed hemorrhoids and showed the reduced incidence of postoperative complications, which was in line with the patient-oriented treatment concept of modern surgery and provided a certain basis for the clinical operation in the treatment of severe prolapsed hemorrhoids. However, due to the small number of cases included in this study, the lack of a large sample with a long-term follow-up and survey, the long-term efficacy and recurrence need to be further evaluated by increasing the sample size, improving the corresponding observation index, and carrying out prospective studies with in-depth analysis.