Ao CB, Wu PL, Shao L, Yu JY, Wu WG. Clinical effect of ultrasound-guided nerve block and dexmedetomidine anesthesia on lower extremity operative fracture reduction. World J Clin Cases 2022; 10(13): 4064-4071 [PMID: 35665104 DOI: 10.12998/wjcc.v10.i13.4064]
Corresponding Author of This Article
Wei-Guo Wu, BMed, Associate Chief Physician, Department of Orthopedics, Taizhou Luqiao Second People’s Hospital, No. 500 Industrial Road, Jinqing Town, Luqiao District, Taizhou 318000, Zhejiang Province, China. wu4628554@163.com
Research Domain of This Article
Anesthesiology
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Cheng-Bin Ao, Ping-Lei Wu, Liang Shao, Jian-Ying Yu, Department of Anesthesiology, The People’s Hospital of Yuhuan, Taizhou 317600, Zhejiang Province, China
Wei-Guo Wu, Department of Orthopedics, Taizhou Luqiao Second People’s Hospital, Taizhou 318000, Zhejiang Province, China
Author contributions: Ao CB and Wu WG designed this retrospective study; Ao CB wrote the manuscript; Ao CB, Lei P, Shao L and Yu JY were responsible for sorting the data; and all authors contributed to the article and approved the submitted version.
Institutional review board statement: The study was approved by the Ethics Committee of Yuhuan City People's Hospital, Taizhou City, Zhejiang Province.
Informed consent statement: Patients were not required to give informed consent to the study because the analysis used anonymous clinical data that were obtained after each patient agreed to treatment by written consent.
Conflict-of-interest statement: Nothing to disclose.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Wei-Guo Wu, BMed, Associate Chief Physician, Department of Orthopedics, Taizhou Luqiao Second People’s Hospital, No. 500 Industrial Road, Jinqing Town, Luqiao District, Taizhou 318000, Zhejiang Province, China. wu4628554@163.com
Received: December 27, 2021 Peer-review started: December 27, 2021 First decision: January 25, 2022 Revised: February 17, 2022 Accepted: March 15, 2022 Article in press: March 15, 2022 Published online: May 6, 2022 Processing time: 123 Days and 18.8 Hours
ARTICLE HIGHLIGHTS
Research background
It is of great importance to develop an effective anesthesia program to effectively ensure the progress of surgery.
Research motivation
This study developed an effective anesthesia program to effectively ensure the progress of surgery.
Research objectives
Discusses the effect of ultrasound-guided nerve block combined with dexmedetomidine anesthesia in lower extremity fracture surgery.
Research methods
A total of 120 patients admitted to our hospital with lower extremity fractures from January 2017 to December 2019 were selected. The control group received an ultrasound-guided nerve block. The observation group was treated with dextromethomidine based on the control group.
Research results
The mean arterial pressure of T1, T2 and T3 in the observation group were significantly higher than that of the control group. The observation group’s heart rate (HR) times at T1 was significantly lower than that of the control group. The times of observation group’s HR at T2 and T3 was significantly higher than that of the control group. The recovery time was significantly lower than that of the control group. Six hours post-anesthesia, epinephrine and norepinephrine in the observation group were significantly lower than that of the control group, and the mini-mental state exam score of the observation group was significantly higher than that in the control group.
Research conclusions
Ultrasound-guided nerve block combined with dexmedetomidine has a good anesthetic effect in the operation of lower limb fractures and has little effect on the hemodynamics of patients.
Research perspectives
We will explore the clinical effect of this method of anesthesia in other operations.
