He LH, Yang B, Su XQ, Zhou Y, Zhang Z. Comparison of clinical efficacy and postoperative inflammatory response between laparoscopic and open radical resection of colorectal cancer. World J Clin Cases 2022; 10(13): 4042-4049 [PMID: 35665125 DOI: 10.12998/wjcc.v10.i13.4042]
Corresponding Author of This Article
Long-Hai He, BM BCh, Associate Chief Physician, Department of General Surgery, The First People's Hospital of Wanzhou District, No. 388 East Tiancheng Road, Wanzhou District, Chongqing 404040, China. helh2021@163.com
Research Domain of This Article
Surgery
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. May 6, 2022; 10(13): 4042-4049 Published online May 6, 2022. doi: 10.12998/wjcc.v10.i13.4042
Comparison of clinical efficacy and postoperative inflammatory response between laparoscopic and open radical resection of colorectal cancer
Long-Hai He, Bo Yang, Xiao-Qin Su, Yue Zhou, Zhen Zhang
Long-Hai He, Bo Yang, Zhen Zhang, Department of General Surgery, The First People’s Hospital of Wanzhou District, Chongqing 404040, China
Xiao-Qin Su, Yue Zhou, Department of Clinical Nutrition, The First People’s Hospital of Wanzhou District, Chongqing 404040, China
Author contributions: He LH and Yang B design the experiment; Su XQ drafted the manuscript; Zhou Y, Zhang Z and He LH collected the data; Yang B and Su XQ analyzed and interpreted data; Zhou Y, Zhang Z and He LH wrote and revised the manuscript.
Institutional review board statement: This study was approved by the First People’s Hospital of Wanzhou District Ethics Committee.
Informed consent statement: Patients were not required to give informed consent to the study because the analysis used anonymous clinical data that were obtained after each patient agreed to treatment by written consent.
Conflict-of-interest statement: The authors declared that there is no conflict of interest between them.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Long-Hai He, BM BCh, Associate Chief Physician, Department of General Surgery, The First People's Hospital of Wanzhou District, No. 388 East Tiancheng Road, Wanzhou District, Chongqing 404040, China. helh2021@163.com
Received: December 1, 2021 Peer-review started: December 1, 2021 First decision: December 27, 2021 Revised: January 18, 2022 Accepted: March 6, 2022 Article in press: March 6, 2022 Published online: May 6, 2022 Processing time: 149 Days and 20.3 Hours
ARTICLE HIGHLIGHTS
Research background
The incidence of colorectal cancer (CRC) is a serious threat to the health and quality of life of patients. In the treatment of CRC, both laparoscopy and radical resection are widely used.
Research motivation
This study provided a reference for CRC treatment.
Research objectives
This study aimed to investigate the clinical efficacy and postoperative inflammatory response of laparoscopic and open radical resection of CRC.
Research methods
A total of 96 patients with CRC from March 2016 to April 2021 were selected, and were divided into the study group (n = 48) and control group (n = 48) using a simple random method.
Research results
The operating time in the study group was longer than that of the control group, but the intraoperative blood loss, recovery time of gastrointestinal function, and hospital stay were better than those in the control group. The incidence of the complications in the study group was lower than that of the control group.
Research conclusions
Laparoscopic radical resection of CRC can reduce surgical trauma, reduce inflammatory response and pain stress response caused by surgical treatment, which is conducive to shortening the rehabilitation of patients, with a low incidence of complications, and good safety.
Research perspectives
Laparoscopic radical resection of CRC can achieve wider clinical application.
