Fang YY, Ni JC, Wang Y, Yu JH, Fu LL. Risk factors for hospital readmissions in pneumonia patients: A systematic review and meta-analysis. World J Clin Cases 2022; 10(12): 3787-3800 [PMID: 35647168 DOI: 10.12998/wjcc.v10.i12.3787]
Corresponding Author of This Article
Ling-Ling Fu, MD, Chief Doctor, Department of Respiratory Medicine, Zhuji Affiliated Hospital of Shaoxing University, No. 9 Jianmin Road, Zhuji 311800, Zhejiang Province, China. fu198609262021@sina.com
Research Domain of This Article
Health Care Sciences & Services
Article-Type of This Article
Meta-Analysis
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Apr 26, 2022; 10(12): 3787-3800 Published online Apr 26, 2022. doi: 10.12998/wjcc.v10.i12.3787
Risk factors for hospital readmissions in pneumonia patients: A systematic review and meta-analysis
Yuan-Yuan Fang, Jian-Chao Ni, Yin Wang, Jian-Hong Yu, Ling-Ling Fu
Yuan-Yuan Fang, Jian-Chao Ni, Jian-Hong Yu, Department of Geriatrics, Affiliated Hospital of Shaoxing University, Shaoxing 312000, Zhejiang Province, China
Yin Wang, Department of Internal Medicine, Yuecheng People’s Hospital, Shaoxing 312000, Zhejiang Province, China
Ling-Ling Fu, Department of Respiratory Medicine, Zhuji Affiliated Hospital of Shaoxing University, Zhuji 311800, Zhejiang Province, China
Author contributions: Fang YY and Ni JC conceived and designed the study; Wang Y and Yu JH were involved in literature search and data collection; Yu JH and Fu LL analyzed the data; Fang YY and Ni JC wrote the paper; Wang Y and Yu JH reviewed and edited the manuscript; all authors read and approved the final manuscript.
Conflict-of-interest statement: The authors deny any conflict of interest.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2020 Checklist, and manuscript was prepared and revised according to the PRISMA 2020 Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ling-Ling Fu, MD, Chief Doctor, Department of Respiratory Medicine, Zhuji Affiliated Hospital of Shaoxing University, No. 9 Jianmin Road, Zhuji 311800, Zhejiang Province, China. fu198609262021@sina.com
Received: November 16, 2021 Peer-review started: November 16, 2021 First decision: January 11, 2022 Revised: January 25, 2022 Accepted: March 16, 2022 Article in press: March 16, 2022 Published online: April 26, 2022
ARTICLE HIGHLIGHTS
Research background
Factors that are associated with the short-term rehospitalization have been investigated previously in numerous studies. However, the majority of these studies have not produced any conclusive results because of their smaller sample sizes, differences in the definition of pneumonia, joint pooling of the in-hospital and post-discharge deaths and lower generalizability.
Research motivation
To the best of our knowledge, there has been no systematic effort to pool data on the risk factors for hospital readmissions in patients with pneumonia.
Research objectives
To pool data from individual studies to identify risk factors for hospital readmissions in patients with pneumonia.
Research methods
Systematic search was conducted in PubMed Central, EMBASE, MEDLINE, Cochrane library, ScienceDirect and Google Scholar databases, and search engines from inception until July 2021.
Research results
In total, 17 studies with over 3 million participants were included. Majority of the studies had good to satisfactory quality as per Newcastle Ottawa scale. Male gender, cancer, heart failure, chronic respiratory disease, chronic kidney disease and diabetes mellitus had statistically significant association with the hospital readmission rate among pneumonia patients.
Research conclusions
Male gender and specific chronic comorbid conditions were found to be significant risk factors for hospital readmission among pneumonia patients. These results may allow clinicians and policymakers to develop better intervention strategies for the patients.
Research perspectives
More longitudinal studies are needed to identify accurate and reliable effect estimates and make evidence-based recommendation for developing potential interventions in hospital setting.
