Randomized Controlled Trial
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Apr 26, 2022; 10(12): 3764-3772
Published online Apr 26, 2022. doi: 10.12998/wjcc.v10.i12.3764
Effect of wrist-ankle acupuncture on propofol dosage during painless colonoscopy: A randomized controlled prospective study
Tao He, Chan Liu, Zhi-Xia Lu, Li-Li Kong, Yan Li, Zhe Xu, Ya-Jing Dong, Wei Hao
Tao He, Chan Liu, Zhi-Xia Lu, Li-Li Kong, Yan Li, Zhe Xu, Ya-Jing Dong, Wei Hao, Department of Anesthesiology, Hebei Provincial Hospital of Traditional Chinese Medicine, Shijiazhuang 050000, Hebei Province, China
Wei Hao, Key Laboratory of Integrated Chinese and Western Medicine for Gastroenterology Research (Hebei), Key Laboratory of Integrated Chinese and Western Medicine for Gastroenterology Research (Hebei), Shijiazhuang 050000, Hebei Province, China
Author contributions: Hao W and Dong YJ conceived the study; Dong YJ, He T and Liu C recruited the patients; Dong YJ performed the wrist-ankle acupuncture; He T, Li Y, Liu C, Xu Z and Lu ZX collected the data; Hao W analyzed the data; Hao W, Kong LL interpreted the data; He T and C Liu contributed equally; All authors read and approved the final version of the manuscript.
Institutional review board statement: This study was approved by the Hebei Provincial Hospital of Traditional Chinese Medicine Medical Ethics Committee (2019-KY-003-02).
Clinical trial registration statement: This study has been registered in China Clinical Trial Registration Center (registration code: ChiCTR1900022177, http://www.chictr.org.cn/).
Informed consent statement: Written informed consent was obtained from the participants for publication of this article and any accompanying tables/images.
Conflict-of-interest statement: The authors declare that there are no conflicts of interest.
Data sharing statement: No additional data are available.
CONSORT 2010 statement: The authors have read the CONSORT 2010 Statement, and the manuscript was prepared and revised according to the CONSORT 2010 Statement.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Wei Hao, MD, Doctor, Professor, Department of Anesthesiology, Hebei Provincial Hospital of Traditional Chinese Medicine, No. 389 Zhongshan East Road, Chang'an District, Shijiazhuang 050000, Hebei Province, China. keyan_66666@126.com
Received: June 26, 2021
Peer-review started: June 26, 2021
First decision: September 1, 2021
Revised: October 14, 2021
Accepted: March 4, 2022
Article in press: March 4, 2022
Published online: April 26, 2022
Processing time: 298 Days and 22 Hours
ARTICLE HIGHLIGHTS
Research background

Propofol is a common choice for painless endoscopic sedation and anesthetics, but it can cause severe respiratory and circulatory depression. Therefore, it is important to find a way to reduce the dose of propofol.

Research motivation

Wrist-ankle acupuncture may reduce propofol dose during colonoscopy.

Research objectives

To determine if control group patients were different from the wrist-ankle acupuncture group regarding advantages in operation time, waking time, incidence of nausea and vomiting, incidence of abdominal distension, pain after colonoscopy, examiner satisfaction, patient satisfaction and Borg fatigue index.

Research methods

During colonoscopy, the wrist-ankle needle was inserted to explore whether the dose of propofol could be reduced. Patient's operation time, waking time, incidence of nausea and vomiting, incidence of abdominal distension, pain after colonoscopy, examiner satisfaction, patient satisfaction and Borg fatigue index during painless colonoscopy were compared between wrist-ankle acupuncture group and the control group.

Research results

Wrist-ankle acupuncture can reduce the induced dose and total dose of propofol, reduce the incidence of adverse reactions of painless colonoscopy and does not affect the satisfaction of the examiner and the patient.

Research conclusions

Wrist-ankle acupuncture combined with propofol can significantly reduce propofol dose during painless colonoscopy, decrease the incidence of adverse drug reactions, reduce the incidence of abdominal distention after examination, improve examiners' satisfaction and safety of colonoscopy and reduce the wake-up time of patients.

Research perspectives

The wrist-ankle needle is simple to operate and can reduce the dosage of propofol, and it is easy to promote in clinical practice.