Retrospective Study
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Apr 26, 2022; 10(12): 3686-3697
Published online Apr 26, 2022. doi: 10.12998/wjcc.v10.i12.3686
Role of multidetector computed tomography in patients with acute infectious colitis
Seung Jung Yu, Jae Hyuk Heo, Eun Jeong Choi, Jong Hyuk Kim, Hong Sub Lee, Sun Young Kim, Jae Hoon Lim
Seung Jung Yu, Jae Hyuk Heo, Eun Jeong Choi, Hong Sub Lee, Department of Internal Medicine, Inje University Busan Paik Hospital, Busan 47392, South Korea
Jong Hyuk Kim, Jae Hoon Lim, Department of Radiology, Myongji Hospital, Hanyang University College of Medicine, Goyang 10475, South Korea
Sun Young Kim, Department of Cancer Control and Population Health, National Cancer Center, Goyang 10408, South Korea
Author contributions: Lee HS and Lim JH designed the research study; Lee HS, Yu SJ, Heo JH and Choi EJ performed the research; Kim SY contributed analytic tools; Yu SJ and Heo JH analyzed the data and wrote the manuscript; and All authors have read and approve the final manuscript.
Supported by the 2019 Inje University research grant.
Institutional review board statement: Ethics committee approval was received for this study from Institutional Review Board of the Myongji hospital (Decision No. MJH 2018-08-020).
Conflict-of-interest statement: The authors have no conflicts of interest to declare.
Data sharing statement: Technical appendix, statistical code, and dataset available from the corresponding author at hslee@paik.ac.kr
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hong Sub Lee, MD, PhD, Professor, Department of Internal Medicine, Inje University Busan Paik Hospital, 75 Bokji-ro, Busanjin-gu, Busan 47392, South Korea. hslee@paik.ac.kr
Received: May 31, 2021
Peer-review started: May 31, 2021
First decision: July 1, 2021
Revised: September 14, 2021
Accepted: March 4, 2022
Article in press: March 4, 2022
Published online: April 26, 2022
Processing time: 324 Days and 12.1 Hours
ARTICLE HIGHLIGHTS
Research background

Multidetector computed tomography (MDCT) findings are well known depending on the etiology of colitis such as ischemic colitis, infectious colitis, and pseudomembranous colitis, but comparison of MDCT findings between bactria and virus infection in infectious colitis has not been studied.

Research motivation

If we can better differentiate between bacterial colitis and viral colitis, we can get help in deciding on a treatment method, such as the use of antibiotics.

Research objectives

This study's objective is to examine the usefulness of MDCT in distinguishing the etiology of acute infectious colitis.

Research methods

The cause of infectious colitis was defined using stool polymerase chain reaction (PCR) test for 244 infectious colitis patients for 4 years, and CT findings according to the cause were compared by using 11 parameters.

Research results

The parameters of bacterial colitis, except for small bowel involvement and comb sign had a significantly higher odds ratio than parameters of viral coltitis.

Research conclusions

MDCT provides many clues that can be useful in suggesting a specific etiology of acute infectious colitis.

Research perspectives

This study had limitations such as retrospective study, selection bias and exception of other cause of colitis, so a large prospective and well-designed study, including protocols—such as MDCT, serology/bacteriology, and endoscopy result—is necessary.