Retrospective Study
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jan 7, 2022; 10(1): 62-70
Published online Jan 7, 2022. doi: 10.12998/wjcc.v10.i1.62
Surgical resection of intradural extramedullary tumors in the atlantoaxial spine via a posterior approach
Di-Hua Meng, Jia-Qi Wang, Kun-Xue Yang, Wei-You Chen, Cheng Pan, Hua Jiang
Di-Hua Meng, Jia-Qi Wang, Kun-Xue Yang, Wei-You Chen, Cheng Pan, Hua Jiang, Department of Spine Surgery, the First Affiliated Hospital of Guangxi Medical University, Nanning 530021, Guangxi Province, China
Author contributions: Jiang H conceived, supervised the study and performed critical revision of the manuscript; Meng DH and Wang JQ were involved in the data search and selection of data; Yang KX, Pan C and Chen WY analyzed and interpreted the data and drafted the manuscript; All authors read and approved the final manuscript.
Supported by the National Natural Science Foundation of China, No. 81860406; Guangxi Natural Science Foundation, No. 2018GXNSFAA281127; and Medical Excellence Award Funded by the Creative Research Development Grant from The First Affiliated Hospital of Guangxi Medical University.
Institutional review board statement: The histological study of surgical samples was approved by the Ethics Committee of the First Affiliated Hospital of Guangxi Medical University (No. 2020-KY-NSFC-025).
Informed consent statement: Written consent was obtained from each participant.
Conflict-of-interest statement: The authors declare that they have no competing interests.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hua Jiang, MD, PhD, Professor, Department of Spine Surgery, the First Affiliated Hospital of Guangxi Medical University, No. 6 Shuangyong Road, Nanning 530021, Guangxi Province, China. drjianghua@163.com
Received: May 3, 2021
Peer-review started: May 3, 2021
First decision: October 16, 2021
Revised: October 30, 2021
Accepted: November 19, 2021
Article in press: November 19, 2021
Published online: January 7, 2022
ARTICLE HIGHLIGHTS
Research perspectives

The goal of new surgical treatments is to reduce the incidence of cerebrospinal fluid leakage and relieve injury to patients.

Research conclusions

Total resection of atlantoaxial intradural extramedullary (IDEM) tumors is feasible and effective via a posterior approach.

Research results

A statistically significant difference was noted between the preoperative Japanese Orthopedic Association score (11.2 ± 1.1) and the score at the last final follow-up (15.6 ± 1.0) (P < 0.05). A statistically significant difference was also noted between the preoperative Nurick grade (2.3 ± 0.9) and that at the last follow-up (1.2 ± 0.4) (P < 0.05). However, no statistically significant difference was noted between the preoperative and last follow-up C1-2 Cobb angle and C2-7 Cobb angle (P > 0.05). No mortalities, severe complications or tumor recurrence were observed during the follow-up period.

Research methods

This was a retrospective study of 13 patients who underwent atlantoaxial IDEM tumor resection via a posterior approach.

Research objectives

To investigate the efficacy of surgical resection for atlantoaxial IDEM tumors and its influencing factors.

Research motivation

To explore the safety and feasibility of atlantoaxial IDEM tumor resection.

Research background

IDEM tumors in the atlantoaxial spine are uncommon and present with progressive pain and neurological deficits.