Case Report
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Mar 6, 2021; 9(7): 1661-1667
Published online Mar 6, 2021. doi: 10.12998/wjcc.v9.i7.1661
Multiple well-differentiated retroperitoneal liposarcomas with different patterns of appearance on computed tomography: A case report
Tian-Hao Xie, Xiang-Xiang Ren, Yan Fu, Si-Ning Ha, Li-Tao Liu, Xiao-Shi Jin
Tian-Hao Xie, Xiang-Xiang Ren, Si-Ning Ha, Li-Tao Liu, Xiao-Shi Jin, Department of General Surgery, Affiliated Hospital of Hebei University, Baoding 071000, Hebei Province, China
Yan Fu, Department of Ophthalmology, Baoding First Central Hospital, Baoding 071000, Hebei Province, China
Author contributions: Xie TH, Ren XX, and Jin XS made substantial contributions to the conception and design of the case report; Xie TH and Jin XS were responsible for the manuscript; Xie TH, Ren XX, Fu Y, Liu LT, and Ha SN collected the samples and confirmed data accuracy; Xie TH, Ren XX, and Fu Y participated in drafting the manuscript; Xie TH, Ha SN, Liu LT, and Jin XS made substantial revisions to the manuscript; all of the authors read and approved the final manuscript.
Supported by Science Technology Plan of Baoding Municipal Department of Science and Technology, No. 1951ZF091
Informed consent statement: Written consent for publication was acquired from the patient, and the signed consent form will be provided upon request.
Conflict-of-interest statement: The authors report no conflicts of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xiao-Shi Jin, MD, PhD, Professor, Department of General Surgery, Affiliated Hospital of Hebei University, No. 212 East Yuhua Road, Baoding 071000, Hebei Province, China. doctorjinxiaoshi@126.com
Received: September 14, 2020
Peer-review started: September 14, 2020
First decision: December 14, 2020
Revised: December 18, 2020
Accepted: January 6, 2021
Article in press: January 6, 2021
Published online: March 6, 2021
Processing time: 167 Days and 18 Hours
Abstract
BACKGROUND

Primary retroperitoneal liposarcoma (PRPLS) is a rare soft tissue tumor with nonspecific clinical symptoms; it has different computed tomography (CT) image features according to pathological types. Some patients with a single tumor have been previously reported in the literature. We present an exceptional case of a PRPLS patient with multiple large tumors exhibiting different patterns of appearance on CT and confirmed as atypical lipomatous tumor/well-differentiated liposarcoma by postoperative pathology.

CASE SUMMARY

A 64-year-old man presented with abdominal distension for 1 year. The patient was diagnosed with PRPLS based on physical examination, laparotomy, ultrasonography, CT scan, and surgery. Both of the tumors were completely resected through surgery and confirmed as atypical lipomatous tumor/well-differentiated liposarcoma by postoperative pathology. The postoperative course was uneventful without recurrence or metastasis, as demonstrated by abdominal-pelvic CT during an 18 mo follow-up.

CONCLUSION

Multiple large Well-differentiated liposarcomas with different patterns of appearance on CT image can occur simultaneously in the same patient, to which more attention should be paid to make an effective differential diagnosis.

Keywords: Retroperitoneal liposarcoma; Soft tissue tumor; Complete resection; Recurrence; Case report

Core Tip: Primary retroperitoneal liposarcoma (PRPLS) is a rare soft tissue tumor with nonspecific clinical symptoms; it has different computed tomography (CT) image features according to pathological types. We present an exceptional case of a PRPLS patient with multiple large tumors exhibiting different patterns of appearance on CT and confirmed as atypical lipomatous tumor/well-differentiated liposarcoma by postoperative pathology. This suggested that more attention should be paid to an effective differential diagnosis of PRPLS with different patterns of appearance on CT.