Li X, Xia WY, Jiang F, Liu DY, Lei SQ, Xia ZY, Wu QP. Review of the risk factors for SARS-CoV-2 transmission. World J Clin Cases 2021; 9(7): 1499-1512 [PMID: 33728294 DOI: 10.12998/wjcc.v9.i7.1499]
Corresponding Author of This Article
Qing-Ping Wu, MD, PhD, Professor, Department of Anaesthesiology, Institute of Anaesthesiology and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1277 Jiefang Avenue, Wuhan 430022, Hubei Province, China. wqp1968@163.com
Research Domain of This Article
Infectious Diseases
Article-Type of This Article
Review
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Xia Li, Qing-Ping Wu, Department of Anaesthesiology, Institute of Anaesthesiology and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, Hubei Province, China
Wei-Yi Xia, Poznan University of Medical Science, Poznan 60-781, Poland
Fang Jiang, Zheng-Yuan Xia, Department of Anesthesiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China
Dan-Yong Liu, Department of Anesthesiology, Affiliated Hospital of Guangdong Medical University, Zhanjiang 524000, Guangdong Province, China
Shao-Qing Lei, Department of Anesthesiology, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei Province, China
Author contributions: Li X and Xia WY conceived the idea for this review; Xia ZY and Wu QP directed the work; Li X drafted the manuscript; Jiang F, Liu DY, and Lei SQ participated in the discussion; Xia ZY and Wu QP revised the manuscript; All authors read and approved the final manuscript.
Supported byNational Key Research and Development Program of China, No. 2018YFC2001900; and National Natural Science Foundation of China, No. 81873952 and No. 81670770.
Conflict-of-interest statement: The authors declare that they have no conflicts of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Qing-Ping Wu, MD, PhD, Professor, Department of Anaesthesiology, Institute of Anaesthesiology and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1277 Jiefang Avenue, Wuhan 430022, Hubei Province, China. wqp1968@163.com
Received: October 27, 2020 Peer-review started: October 27, 2020 First decision: December 8, 2020 Revised: December 22, 2020 Accepted: January 22, 2021 Article in press: January 22, 2021 Published online: March 6, 2021 Processing time: 124 Days and 17.5 Hours
Abstract
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, which has lasted for nearly a year, has made people deeply aware of the strong transmissibility and pathogenicity of SARS-CoV-2 since its outbreak in December 2019. By December 2020, SARS-CoV-2 had infected over 65 million people globally, resulting in more than 1 million deaths. At present, the exact animal origin of SARS-CoV-2 remains unclear and antiviral vaccines are now undergoing clinical trials. Although the social order of human life is gradually returning to normal, new confirmed cases continue to appear worldwide, and the majority of cases are sporadic due to environmental factors and lax self-protective consciousness. This article provides the latest understanding of the epidemiology and risk factors of nosocomial and community transmission of SARS-CoV-2, as well as strategies to diminish the risk of transmission. We believe that our review will help the public correctly understand and cope with SARS-CoV-2.
Core Tip: The coronavirus disease 2019 pandemic has not only placed a heavy burden on the health system but has also led to significant sociological, psychological, and economic adverse effects globally. A comprehensive understanding is needed of the risk factors of transmission of severe acute respiratory syndrome coronavirus 2 and strategies to diminish this risk. At the same time, people need to act in a socially responsible and cohesive manner, thus creating a common living space with a low risk of infection.