Published online Feb 26, 2021. doi: 10.12998/wjcc.v9.i6.1455
Peer-review started: November 4, 2020
First decision: December 13, 2020
Revised: December 13, 2020
Accepted: December 27, 2020
Article in press: December 27, 2020
Published online: February 26, 2021
Almost 80 percent of adults in the United States have had cytomegalovirus (CMV) infection by age 40. The number of symptomatic CMV hepatitis cases has been increasing along with non-alcoholic fatty liver disease (NAFLD) cases in the United States that is estimated to be 25 percent of the population. In this paper, we try to link these two entities together.
In this case report, we describe a young female who presented with fever, nausea, and vomiting who was found to have NAFLD and CMV hepatitis that was treated supportively.
In this case report, we describe NAFLD as a risk factor for CMV hepatitis and discuss the possible impact on clinical practice. We believe, it is essential to consider NAFLD and it’s disease mechanisms’ localized immu-nosuppression, as a risk factor of CMV hepatitis and severe coronavirus disease 2019 infection.
Core Tip: It is essential to consider non-alcoholic fatty liver disease and it’s disease mechanisms’ localized immunosuppression, as a risk factor of cytomegalovirus hepatitis and possible other viral diseases. Also, with non-alcoholic fatty liver disease raising numbers it is worthwhile to screen for it in high risk population to prevent from it's complications and risks to develop severe viral diseases in case of infection that could be life threatening.