Ban B, Zhang K, Li JN, Liu TJ, Shi J. Ductal breast carcinoma metastasized to the rectum: A case report and review of the literature. World J Clin Cases 2021; 9(36): 11346-11354 [PMID: 35071565 DOI: 10.12998/wjcc.v9.i36.11346]
Corresponding Author of This Article
Jian Shi, MD, PhD, Surgical Oncologist, Department of General Surgery, The Second Hospital of Jilin University, No. 218 Ziqiang Street, Nanguan District, Changchun 130041, Jilin Province, China. dr.shi@live.cn
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Dec 26, 2021; 9(36): 11346-11354 Published online Dec 26, 2021. doi: 10.12998/wjcc.v9.i36.11346
Ductal breast carcinoma metastasized to the rectum: A case report and review of the literature
Bo Ban, Kai Zhang, Jian-Nan Li, Tong-Jun Liu, Jian Shi
Bo Ban, Kai Zhang, Jian-Nan Li, Tong-Jun Liu, Jian Shi, Department of General Surgery, The Second Hospital of Jilin University, Changchun 130041, Jilin Province, China
Author contributions: Ban B was the patient’s surgeon, reviewed the literature and contributed to manuscript drafting; Shi J, Li JN, Zhang K and Liu TJ were responsible for the revision of the manuscript for important intellectual content; all authors issued final approval for the version to be submitted.
Supported byScience and Technology Development Project of Jilin Province, No. 2020SCZT079.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflicts of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jian Shi, MD, PhD, Surgical Oncologist, Department of General Surgery, The Second Hospital of Jilin University, No. 218 Ziqiang Street, Nanguan District, Changchun 130041, Jilin Province, China. dr.shi@live.cn
Received: April 25, 2021 Peer-review started: April 25, 2021 First decision: June 24, 2021 Revised: July 8, 2021 Accepted: August 24, 2021 Article in press: August 24, 2021 Published online: December 26, 2021 Processing time: 242 Days and 0.9 Hours
Abstract
BACKGROUND
Gastrointestinal (GI) metastasis from breast cancer (BC) is rarely encountered in clinical practice. Nonspecific symptoms and long intervals make early diagnosis difficult. Therefore, increased awareness of GI metastasis secondary to BC and a deep understanding of the clinical and pathological features, and intervention for GI metastasis are fundamental to avoid delay in correct diagnosis and management.
CASE SUMMARY
The present report discusses the case of a Chinese female patient aged 36 years. The patient presented with difficult defecation along with bloody stools and hypogastralgia. In 2015, she had undergone right modified radical mastectomy and axillary lymph node dissection in another hospital to treat the infiltrating ductal breast carcinoma pT1N1M0. The presenting symptoms were investigated by colonoscopy, which indicated a circumferential stricture in the lower rectum at 3 cm from the anal edge. Further investigation with positron emission tomography-computed tomography revealed an uptake of fluorodeoxyglucose within the distal rectum as well as in the left acetabulum. The samples from laparoscopic exploration were biopsied, which revealed metastases of BC. Immunohistochemical analysis of the tumor confirmed that the patient had rectal metastasis of infiltrating ductal BC.
CONCLUSION
Rectal metastasis should be considered when patients with a history of BC present with changed bowel habits.
Core Tip: Rectal metastasis of infiltrating ductal breast cancer has a low incidence. For patients with a history of breast cancer with digestive complaints, bowel metastasis must be considered.
