Case Report
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Dec 16, 2021; 9(35): 11102-11107
Published online Dec 16, 2021. doi: 10.12998/wjcc.v9.i35.11102
Ventricular fibrillation and sudden cardiac arrest in apical hypertrophic cardiomyopathy: Two case reports
Yae Min Park, Albert Youngwoo Jang, Wook-Jin Chung, Seung Hwan Han, Christopher Semsarian, In Suck Choi
Yae Min Park, Albert Youngwoo Jang, Wook-Jin Chung, Seung Hwan Han, In Suck Choi, Department ofCardiology, Gachon University Gil Medical Center, Incheon 21556, South Korea
Christopher Semsarian, Agnes Ginges Centre for Molecular Cardiology Centenary Institute, The University of Sydney, Sydney 21556, Australia
Author contributions: Park YM and Semsarian C conceptualized the study; Jang AY, Chung WJ, and Han SH performed the data analysis; Semsarian C and Park YM supervised the study; Park YM wrote the original draft; Park YM, Semsarian C and Choi IS reviewed and edited the manuscript.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yae Min Park, MD, PhD, Associate Professor, Department of Cardiology, Gachon University Gil Medical Center, 774-21 Namdong Daero, Namdonggu, Incheon 21556, South Korea. ypruimin@gmail.com
Received: July 20, 2021
Peer-review started: July 20, 2021
First decision: September 28, 2021
Revised: October 12, 2021
Accepted: October 27, 2021
Article in press: October 27, 2021
Published online: December 16, 2021
Processing time: 142 Days and 23.6 Hours
Abstract
BACKGROUND

Apical hypertrophic cardiomyopathy (HCM) is considered to have a benign prognosis in terms of cardiovascular mortality. This serial case report aimed to raise awareness of ventricular fibrillation (VF) and sudden cardiac death (SCD) in apical HCM.

CASE SUMMARY

Here we describe two rare cases of apical HCM that presented with documented VF and sudden cardiac collapse. These patients were previously not recommended for primary prevention using implantable cardioverter-defibrillator (ICD) therapy based on current guidelines. However, both received ICD therapy for the secondary prevention of SCD.

CONCLUSION

These cases illustrate serious complications including VF and aborted sudden cardiac arrest in apical HCM patients who are initially not candidates for primary prevention using ICD implantation based on current guidelines.

Keywords: Apical hypertrophic cardiomyopathy; Ventricular fibrillation; Implantable cardioverter-defibrillator; Case report

Core Tip: Apical hypertrophic cardiomyopathy (HCM) is a rare form of non-obstructive HCM. It has a benign prognosis in terms of cardiovascular mortality. Here we describe two rare cases of apical HCM that presented as documented ventricular fibrillation (VF) and sudden cardiac collapse. Although apical HCM has a typically benign prognosis, clinicians must consider that VF can occur and lead to sudden cardiac arrest.