Retrospective Study
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Oct 6, 2021; 9(28): 8358-8365
Published online Oct 6, 2021. doi: 10.12998/wjcc.v9.i28.8358
Short-term effect and long-term prognosis of neuroendoscopic minimally invasive surgery for hypertensive intracerebral hemorrhage
Jian-Hui Wei, Ya-Nan Tian, Ya-Zhao Zhang, Xue-Jing Wang, Hong Guo, Jian-Hui Mao
Jian-Hui Wei, Department of Neurosurgery, Harrison International Peace Hospital, Hengshui 053000, Hebei Province, China
Ya-Nan Tian, Ya-Zhao Zhang, Xue-Jing Wang, Hong Guo, Jian-Hui Mao, Department of Neurology, Harrison International Peace Hospital, Hengshui 053000, Hebei Province, China
Author contributions: Wei JH and Tian YN design the experiment; Zhang YZ drafted the work; Wang XJ, Guo H and Mao JH collected the data; Wei JH and Tian YN analysed and interpreted data; Wei JH, Tian YN and Zhang YZ wrote the article.
Institutional review board statement: This study was approved by the Harrison International Peace Hospital Ethics Committee.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: The author declares that there is no conflict of interest between them.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jian-Hui Mao, MD, Chief Doctor, Department of Neurology, Harrison International Peace Hospital, No. 180 Renmin East Road, Taocheng District, Hengshui 053000, Hebei Province, China. weijianhui2005@126.com
Received: May 27, 2021
Peer-review started: May 27, 2021
First decision: June 24, 2021
Revised: July 2, 2021
Accepted: August 5, 2021
Article in press: August 5, 2021
Published online: October 6, 2021
Abstract
BACKGROUND

Hypertensive intracerebral hemorrhage is a common critical disease of the nervous system, comprising one fifth of all acute cerebrovascular diseases and has a high disability and mortality rate. It severely affects the patients’ quality of life.

AIM

To analyze the short-term effect and long-term prognosis of neuroendoscopic minimally invasive surgery for hypertensive intracerebral hemorrhage.

METHODS

From March 2018 to May 2020, 118 patients with hypertensive intracerebral hemorrhage were enrolled in our study and divided into a control group and observation group according to the surgical plan. The control group used a hard-channel minimally invasive puncture and drainage procedure. The observation group underwent minimally invasive neuroendoscopic surgery. The changes in the levels of serum P substances (SP), inflammatory factors [tumor necrosis factor-α, interleukin-6 (IL-6), IL-10], and the National Hospital Stroke Scale (NIHSS) and Barthel index scores were recorded. Surgery related indicators and prognosis were compared between the two groups.

RESULTS

The operation time (105.26 ± 28.35) of the observation group was min longer than that of the control group, and the volume of intraoperative bleeding was 45.36 ± 10.17 mL more than that of the control group. The hematoma clearance rates were 88.58% ± 4.69% and 94.47% ± 4.02% higher than those of the control group at 48 h and 72 h, respectively. Good prognosis rate (86.44%) was higher in the observation group than in the control group, and complication rate (5.08%) was not significantly different from that of the control group (P > 0.05).The SP level and Barthel index score of the two groups increased (P < 0.05) and the inflammatory factors and NIHSS score decreased (P < 0.05). The cytokine levels, NIHSS score, and Barthel index score were better in the observation group than in the control group (P < 0.05).

CONCLUSION

Neuroendoscopic minimally invasive surgery is more complicated than hard channel minimally invasive puncture drainage in the treatment of hypertensive intracerebral hemorrhage; however, hematoma clearance is more thorough, and the short-term effect and long-term prognosis are better than hard channel minimally invasive puncture drainage.

Keywords: Neuroendoscopic minimally invasive surgery, Hard-channel minimally invasive puncture drainage, Hypertensive intracerebral hemorrhage, Prognosis Hematoma clearance

Core Tip: By comparing the surgical effects of hard channel minimally invasive drainage and neuroendoscopic minimally invasive surgery in hypertensive cerebral hemorrhage, it is confirmed that the latter is relatively complicated compared with the former, but the hematoma is removed more thoroughly and the prognosis is better.